101774-26-9

Basic information

• Product Name: Isoxazole, 4-bromo-3-phenyl-
• CAS NO: 101774-26-9
• Molecular Formula: C9H6BrNO
• Molecular Weight: 224.057
• Mol File: 101774-26-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Isoxazole, 4-bromo-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Isoxazole, 4-bromo-3-phenyl-(101774-26-9)
• EPA Substance Registry System: Isoxazole, 4-bromo-3-phenyl-(101774-26-9)

Safety Data

• Hazardous Substances Data: 101774-26-9(Hazardous Substances Data)

Upstream product

• 1794-48-5 1-bromo-3-phenylprop-2-yne 
• 188720-10-7 2-(3-Phenyl-prop-2-ynyloxy)-isoindole-1,3-dione 
• 149649-90-1 O-(3-phenyl-2-propynyl)hydroxylamine 
• 1504-58-1 3-Phenyl-2-propyn-1-ol 
• 1287769-00-9 benzyl 2,5-dihydro-4-iodo-3-phenyl-2H-isoxazole-2-carboxylate 
• 1287768-62-0 benzyl (3-phenyl-2-propynyl)oxycarbamate 
• 1006-65-1 3-phenylisoxazole 

Relevant articles and documents

Iodocyclization of hydroxylamine derivatives based on the control of oxidative aromatization leading to 2,5-dihydroisoxazoles and isoxazoles

An efficient method for the synthesis of 2,5-dihydroisoxazoles and isoxazoles using iodocyclization of N-alkoxycarbonyl O-propargylic hydroxylamines has been developed. 2,5-Dihydro-4-iodoisoxazole underwent the cross-coupling reactions without aromatization to afford polyfunctionalized 2,5-dihydroisoxazoles. This process was applied to the preparation of valdecoxib and its 2,5-dihydro-derivative.