188720-10-7

Basic information

• Product Name: 2-(3-Phenyl-prop-2-ynyloxy)-isoindole-1,3-dione
• Synonyms: 2-(3-Phenyl-prop-2-ynyloxy)-isoindole-1,3-dione
• CAS NO: 188720-10-7
• Molecular Weight: 277.279
• Mol File: 188720-10-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-(3-Phenyl-prop-2-ynyloxy)-isoindole-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-Phenyl-prop-2-ynyloxy)-isoindole-1,3-dione(188720-10-7)
• EPA Substance Registry System: 2-(3-Phenyl-prop-2-ynyloxy)-isoindole-1,3-dione(188720-10-7)

Safety Data

• Hazardous Substances Data: 188720-10-7(Hazardous Substances Data)

Upstream product

• 108-86-1 bromobenzene 
• 1504-58-1 3-Phenyl-2-propyn-1-ol 
• 524-38-9 N-hydroxyphthalimide 
• 1794-48-5 1-bromo-3-phenylprop-2-yne 

Downstream Products

• 101774-26-9 4-bromo-3-phenylisoxazole 
• 23253-50-1 4-iodo-3-phenylisoxazole 
• 1287768-62-0 benzyl (3-phenyl-2-propynyl)oxycarbamate 
• 1287768-98-2 C₁₂H₁₃NO₃ 
• 1287769-00-9 benzyl 2,5-dihydro-4-iodo-3-phenyl-2H-isoxazole-2-carboxylate 
• 1287769-01-0 C₁₂H₁₂INO₃ 
• 1287769-02-1 C₁₃H₁₄INO₃ 
• 1287769-03-2 C₁₄H₁₆INO₃ 
• 1287769-04-3 C₂₄H₁₈INO₃ 
• 1287768-63-1 isopropyl (3-phenyl-2-propynyl)oxycarbamate 
• 1287768-99-3 C₂₄H₁₉NO₃ 
• 1287769-31-6 benzyl 2,5-dihydro-3-phenyl-4-((trimethylsilyl)ethynyl)-2H-isoxazole-2-carboxylate 
• 1287769-32-7 benzyl 2,5-dihydro-3-phenyl-4-(2-thienyl)-2H-isoxazole-2-carboxylate 
• 1287769-33-8 benzyl 2,5-dihydro-4-((E)-2-(methoxycarbonyl)ethenyl)-3-phenyl-2H-isoxazole-2-carboxylate 

Relevant articles and documents

Alkyne Cycloadditions Mediated by Tetrabutylammonium Fluoride: A Unified and Diversifiable Route to Isoxazolines and Pyrazolines

A versatile approach to isoxazolines and pyrazolines by the cyclization of alkyne substrates using tetrabutylammonium fluoride (TBAF) is described. The reported diheteroatom cycles were produced under mild reaction conditions and with broad product scope.

Design and synthesis of m1-selective muscarinic agonists: (R)-(-)-(Z)- 1-azabicyclo[2.2.1]heptan-3-one, O-(3-(3'-methoxyphenyl)-2-propynyl)-oxime maleate (CI-1017), a functionally m1-selective muscarinic agonist

The synthesis and SAR of a series of (Z)-(±)-1- azabicyclo[2.2.1]heptan-3-one, O-(3-aryl-2-propynyl)oximes are described. The biochemistry and pharmacology of 24Z (PD 142505) and its enantiomers are highlighted. 24Z is functionally an m1-selective muscari