101787-42-2

Upstream product

• 591-50-4 iodobenzene 
• 100-42-5 styrene 
• 6069-06-3 2-iodoethyl ethyl ether 
• 23665-09-0 phenylzinc iodide 
• 36865-40-4 1-bromo-3-ethoxypropane 

Downstream Products

• 102756-09-2 1,7-diethoxy-4,4-diphenyl-heptane 
• 102953-65-1 5,5-diphenyl-nonanedioic acid diethyl ester 
• 102655-62-9 2-oxo-6,6-diphenyl-cyclooctanecarboxylic acid ethyl ester 
• 111663-83-3 5,5-diphenyl-nonanedioic acid 
• 102447-40-5 2-Hydroxy-6,6-diphenyl-cyclononanon 
• 102448-21-5 6,6-diphenyl-cyclononane-1,2-dione 
• 102163-77-9 1,7-diiodo-4,4-diphenyl-heptane 
• 109865-53-4 4,4-diphenyl-heptane 
• 113251-55-1 5,5-diphenyl-nonanedinitrile 

Relevant academic research and scientific papers

Ni-Catalyzed Regioselective Alkylarylation of Vinylarenes via C(sp3)-C(sp3)/C(sp3)-C(sp2) Bond Formation and Mechanistic Studies

We report a Ni-catalyzed regioselective alkylarylation of vinylarenes with alkyl halides and arylzinc reagents to generate 1,1-diarylalkanes. The reaction proceeds well with primary, secondary and tertiary alkyl halides, and electronically diverse arylzinc reagents. Mechanistic investigations by radical probes, competition studies and quantitative kinetics reveal that the current reaction proceeds via a Ni(0)/Ni(I)/Ni(II) catalytic cycle by a rate-limiting direct halogen atom abstraction via single electron transfer to alkyl halides by a Ni(0)-catalyst.