1017968-13-6

Basic information

• Product Name: C₆₃H₁₀₂O₂₈
• Synonyms: C₆₃H₁₀₂O₂₈
• CAS NO: 1017968-13-6
• Molecular Weight: 1307.49
• Mol File: 1017968-13-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₆₃H₁₀₂O₂₈(CAS DataBase Reference)
• NIST Chemistry Reference: C₆₃H₁₀₂O₂₈(1017968-13-6)
• EPA Substance Registry System: C₆₃H₁₀₂O₂₈(1017968-13-6)

Safety Data

• Hazardous Substances Data: 1017968-13-6(Hazardous Substances Data)

Upstream product

• 852628-93-4 3,4,5-tris(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)benzyl chloride 
• 885473-88-1 (3,4,5-tris(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)-phenyl)methanol 
• 852628-92-3 methyl 3,4,5-tris(2-(2-(2-methoxyethoxy)ethoxy)-ethoxy)benzoate 
• 62921-74-8 2-(2-(2-methoxyethoxy)ethoxy)ethyl p-toluenesulfonate 
• 99-24-1 methyl galloate 
• 1017967-79-1 C₆₄H₁₀₄O₂₈ 

Downstream Products

• 1017968-12-5 C₁₁₇H₁₇₁N₅O₃₇ 

Relevant articles and documents

The self-assembly of cystine-bridged γ-peptide-based cyclic peptide-dendron hybrids

Novel cystine-bridged γ-peptide-based cyclic peptide-dendron hybrids have been synthesized by oxidative coupling between two cysteine residues of the linear peptides via the formation of disulfide bonds in high yields. The self-assembly of the hybrids was

Synthesis and characterization of a highly stable dendritic catechol-tripod bearing technetium-99m

The synthesis and preliminary biological tests (in vitro toxicity, in vitro stability) of new Tc(iii)-radiolabelled dendro-chelates are presented. A dendritic 99mTc chelate 1 derived from a pre-organized tripodal tris-catecholamide exhibits a kinetic stability by far more important than its corresponding diethylenetriamine pentaacetic acid (DTPA) homologue 2. This permitted an assessment of the real impact of the pre-organized tripodal structure on kinetic inertness (and thus toxicity), an important issue to address when considering in vivo applications. Radiolabelling was performed using the stannous chloride reduction method; while DTPA-homologue 2 showed a high radiolabelling efficiency (96% radiolabelling yield after 30 min), tripodal complex 1 induced a 93% complexation yield after 45 min. In contrast, radiocomplex 1 derived from the most rigid and organized structure has a higher kinetic stability than 2. Indeed, while dissociation of 2 reached 50% after 1 h 30 min in physiological media like phosphate buffer saline (PBS) and bovine serum albumin (BSA), over 80% of 1 remained stable during the half-life of the radionucleide (6.02 h for 99mTc). Measurements of the cell leakage resulting from membrane damage of neuronal cells treated with increasing concentrations of dendritic ligand 16, together with pictures of treated neurons after staining, showed no detectable toxicity.