1018125-39-7

Basic information

• Product Name: 6-Aminopyrazolo[1,5-a]pyrimidine
• Synonyms: 6-Aminopyrazolo[1,5-a]pyrimidine
• CAS NO: 1018125-39-7
• Molecular Formula: C₆H₆N₄
• Molecular Weight: 134
• Mol File: 1018125-39-7.mol

Chemical Properties

• Appearance: /
• Density: 1.50±0.1 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 0.80±0.30(Predicted)
• CAS DataBase Reference: 6-Aminopyrazolo[1,5-a]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Aminopyrazolo[1,5-a]pyrimidine(1018125-39-7)
• EPA Substance Registry System: 6-Aminopyrazolo[1,5-a]pyrimidine(1018125-39-7)

Safety Data

• Hazardous Substances Data: 1018125-39-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
6-Aminopyrazolo[1,5-a]pyrimidine is used as a key building block for the development of pharmaceuticals. Its unique structure allows for the creation of new compounds with specific properties, contributing to the advancement of drug discovery and medicinal chemistry.
Used in Agrochemical Development:
In the agrochemical industry, 6-Aminopyrazolo[1,5-a]pyrimidine is utilized as a fundamental component in the synthesis of various agrochemicals. Its incorporation aids in the development of innovative products designed to enhance crop protection and improve agricultural yields.
Used in Organic Compound Synthesis:
6-Aminopyrazolo[1,5-a]pyrimidine is employed as a versatile building block in the synthesis of a wide range of organic compounds. Its ability to be modified and combined with other chemical entities enables the creation of diverse molecules with tailored properties for various applications.
Used as a Research Tool in Biological Processes:
6-Aminopyrazolo[1,5-a]pyrimidine also serves as an essential research tool in the study of biological processes. Its unique chemical properties make it suitable for investigating various biological phenomena and contributing to a deeper understanding of life sciences.
Used in Drug Discovery:
As a research tool, 6-Aminopyrazolo[1,5-a]pyrimidine plays a crucial role in drug discovery. Its ability to be structurally modified allows researchers to explore new avenues for the development of potential therapeutic agents, accelerating the process of identifying novel drugs with improved efficacy and safety profiles.

Upstream product

• 55405-65-7 6-Nitropyrazolo<1,5-a>pyrimidine 

Downstream Products

• 1269515-87-8 2,6-difluoro-3-(propylsulfonamido)-N-(pyrazolo[1,5-a]pyrimidin-6-yl)benzamide 

Relevant articles and documents

Potent and selective pyrazolo[1,5-a]pyrimidine based inhibitors of B-RafV600E kinase with favorable physicochemical and pharmacokinetic properties

Herein we describe a novel series of ATP competitive B-Raf inhibitors based on the pyrazolo[1,5-a]pyrimidine scaffold. These inhibitors exhibit both excellent cellular potency and striking B-Raf selectivity. Optimization led to the identification of compound 17, a potent, selective and orally available agent with improved physicochemical and pharmacokinetic properties.