1018143-51-5

Basic information

• Product Name: 2-Methylpyrazolo[1,5-a]pyrimidin-6-amine
• Synonyms: 2-Methylpyrazolo[1,5-a]pyrimidin-6-amine
• CAS NO: 1018143-51-5
• Molecular Formula: C₇H₈N₄
• Molecular Weight: 148.16522
• Mol File: 1018143-51-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Methylpyrazolo[1,5-a]pyrimidin-6-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Methylpyrazolo[1,5-a]pyrimidin-6-amine(1018143-51-5)
• EPA Substance Registry System: 2-Methylpyrazolo[1,5-a]pyrimidin-6-amine(1018143-51-5)

Safety Data

• Hazardous Substances Data: 1018143-51-5(Hazardous Substances Data)

Upstream product

• 80772-95-8 2-Methyl-6-nitro-pyrazolo[1,5-a]pyrimidine 

Downstream Products

• 1269515-86-7 2,6-difluoro-N-(2-methylpyrazolo[1,5-a]pyrimidin-6-yl)-3-(propylsulfonamido)benzamide 

Relevant articles and documents

Potent and selective pyrazolo[1,5-a]pyrimidine based inhibitors of B-RafV600E kinase with favorable physicochemical and pharmacokinetic properties

Herein we describe a novel series of ATP competitive B-Raf inhibitors based on the pyrazolo[1,5-a]pyrimidine scaffold. These inhibitors exhibit both excellent cellular potency and striking B-Raf selectivity. Optimization led to the identification of compound 17, a potent, selective and orally available agent with improved physicochemical and pharmacokinetic properties.