101861-63-6

Basic information

• Product Name: 4,6-Dichloro-1H-indole-2-carboxylic acid
• Synonyms: 4,6-DICHLORO-1H-INDOLE-2-CARBOXYLIC ACID;4,6-DICHLOROINDOLE-2-CARBOXYLIC ACID;4,6-Dicloroindole-2-carboxylic acid;4,6-Dicloroindole-2-Carboxylic;4,6-Dichloroindole-2-carboxylic;MDL 29951;1H-Indole-2-carboxylicacid, 4,6-dichloro-
• CAS NO: 101861-63-6
• Molecular Formula: C₉H₅Cl₂NO₂
• Molecular Weight: 230.05
• Product Categories: Indoles and derivatives;Indole;Organic acids;Indoles
• Mol File: 101861-63-6.mol
• Article Data: 6

Chemical Properties

• Melting Point: 238-239 °C
• Boiling Point: 476.9 °C at 760 mmHg
• Flash Point: 242.2 °C
• Appearance: /
• Density: 1.663 g/cm³
• Vapor Pressure: 6.64E-10mmHg at 25°C
• Refractive Index: 1.73
• Storage Temp.: 2-8°C
• Solubility: DMSO (Slightly, Methanol (Slightly, Heated)
• PKA: 4.10±0.30(Predicted)
• CAS DataBase Reference: 4,6-Dichloro-1H-indole-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-Dichloro-1H-indole-2-carboxylic acid(101861-63-6)
• EPA Substance Registry System: 4,6-Dichloro-1H-indole-2-carboxylic acid(101861-63-6)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 101861-63-6(Hazardous Substances Data)

Usage

Uses

MDL 29951 is an allosteric inhibitor of the enzyme fructose 1,6-bisphosphatase.

InChI:InChI=1/C9H5Cl2NO2/c10-4-1-6(11)5-3-8(9(13)14)12-7(5)2-4/h1-3,12H,(H,13,14)

Upstream product

• 53995-82-7 4,6-dichloro-indole-2-carboxylic acid,ethyl ester 
• 4792-68-1 ethyl 2-(2-(2,4-dichlorophenyl)hydrazono)propanoate 
• 554-00-7 2,4-Dichloroaniline 
• 103855-01-2 ethyl 2-[2-(3,5-dichlorophenyl)hydrazinylidene]propanoate 
• 39943-56-1 3,5-dichlorophenylhydrazine 
• 626-43-7 3,5-Dichloroaniline 

Downstream Products

• 1473450-60-0 NITD-304 
• 306937-25-7 4,6-dichloro-1H-indole-2-carbonyl chloride 
• 101495-18-5 4,6-dichloro-1H-indole 

Relevant articles and documents

3-(2-Carboxyindol-3-yl)propionic Acid Derivatives: Antagonists of the Strychnine-Insensitive Glycine Receptor Associated with the N-Methyl-D-aspartate Receptor Complex

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SPIROCYCLE COMPOUNDS AND METHODS OF MAKING AND USING SAME

Provided herein are compounds and compositions useful as modulators of MAGL. Furthermore, the subject compounds and compositions are useful for the treatment of pain.

N-acyl sulfamide FBPase inhibitor, preparation method thereof, drug composition and application

The invention discloses an N-acryl sulfamide FBPase inhibitor of a novel structure, and a preparation method thereof, a drug composition and an application, and particularly relates to an N-acryl sulfamide FBPase inhibitor shown in the formula I, a salt thereof for medicine, a preparation method, a composition comprising one or more compounds, an application of the compound in preparing the FBPase inhibitor or a drug for treating FBPase-related diseases, and an application in preparing a drug for preventing and/or treating diabetes. The formula is shown in the description.