1018678-50-6 Usage
Description
2-(Difluoromethyl)benzaldehyde is a chemical compound characterized by the molecular formula C8H6F2O. It exists as a colorless liquid with a distinctively strong, sweet aroma. 2-(Difluoromethyl)benzaldehyde is recognized for its high reactivity and is acknowledged to be toxic if ingested or inhaled, potentially causing respiratory irritation and damage. Due to its properties, it necessitates careful handling and adherence to safety protocols during its use.
Uses
Used in Pharmaceutical Industry:
2-(Difluoromethyl)benzaldehyde serves as a crucial intermediate in the synthesis of various pharmaceuticals. Its unique chemical structure allows it to be a building block for the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(Difluoromethyl)benzaldehyde is utilized as an intermediate for the production of pesticides and other agrochemicals. Its reactivity and stability make it suitable for creating compounds that can protect crops from pests and diseases.
Used in Perfume and Fragrance Industry:
2-(Difluoromethyl)benzaldehyde is employed in the creation of perfumes and fragrances due to its strong, sweet scent. It adds depth and complexity to the olfactory profiles of these products, enhancing their appeal and longevity.
Given the compound's potential toxicity and reactivity, it is imperative that safety measures are strictly followed during its production, handling, and application to ensure the well-being of individuals and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 1018678-50-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,1,8,6,7 and 8 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1018678-50:
(9*1)+(8*0)+(7*1)+(6*8)+(5*6)+(4*7)+(3*8)+(2*5)+(1*0)=156
156 % 10 = 6
So 1018678-50-6 is a valid CAS Registry Number.
1018678-50-6Relevant articles and documents
PYRIDAZINONES AND METHODS OF USE THEREOF
-
, (2019/04/11)
Disclosed are compounds according to Formula (A), and related tautomers and pharmaceutical compositions. Also disclosed are therapeutic methods, e.g., of treating kidney diseases, using the compounds of Formula (A).
Access to Difluoromethylated Arenes by Pd-Catalyzed Reaction of Arylboronic Acids with Bromodifluoroacetate
Feng, Zhang,Min, Qiao-Qiao,Zhang, Xingang
supporting information, p. 44 - 47 (2016/01/15)
An unprecedented example of Pd-catalyzed difluoromethylation of aryl boronic acids with bromodifluoroacetate is described. The reaction proceeds under mild reaction conditions with hydroquinone and Fe(acac)3 as additives. Preliminary mechanistic studies reveal that a difluorocarbene pathway is involved in the reaction, which is unusual compared to the most traditional approaches. This reaction has advantages of high efficiency and excellent functional group compatibility, even toward bromide and hydroxy group, thus providing a useful protocol for drug discovery and development.
Copper-mediated difluoromethylation of (hetero)aryl iodides and β-styryl halides with tributyl(difluoromethyl)stannane
Prakash, G. K. Surya,Ganesh, Somesh K.,Jones, John-Paul,Kulkarni, Aditya,Masood, Kamil,Swabeck, Joseph K.,Olah, George A.
supporting information, p. 12090 - 12094 (2013/01/16)
Owing to their unique properties, molecules containing the difluoromethyl group (CF2H) are of great interest. Tributyl(difluoromethyl)stannane has now been used for the selective and efficient direct ipso difluoromethylation of aryl iodides, he
