1018683-94-7

Basic information

• Product Name: 2-[(2R,3aR,7R)-4-oxo-7-phenylhexahydroisoxazolo[3,2-c][1,4]oxazin-2-yl]isoindoline-1,3-dione
• CAS NO: 1018683-94-7
• Molecular Weight: 364.357
• Mol File: 1018683-94-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[(2R,3aR,7R)-4-oxo-7-phenylhexahydroisoxazolo[3,2-c][1,4]oxazin-2-yl]isoindoline-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(2R,3aR,7R)-4-oxo-7-phenylhexahydroisoxazolo[3,2-c][1,4]oxazin-2-yl]isoindoline-1,3-dione(1018683-94-7)
• EPA Substance Registry System: 2-[(2R,3aR,7R)-4-oxo-7-phenylhexahydroisoxazolo[3,2-c][1,4]oxazin-2-yl]isoindoline-1,3-dione(1018683-94-7)

Safety Data

• Hazardous Substances Data: 1018683-94-7(Hazardous Substances Data)

Upstream product

• 3485-84-5 N-vinylphthalimide 
• 182316-01-4 (5R)-5,6-dihydro-5-phenyl-2H-1,4-oxazin-2-one-N-oxide 

Relevant articles and documents

1,3-Dipolar cycloaddition of N-substituted dipolarophiles and nitrones: Highly efficient solvent-free reaction

(Chemical Equation Presented) New isoxazolidines were synthesized in good to excellent yields by 1,3-dipolar cycloaddition of N-vinylamide dipolarophiles and nitrones. Strikingly, solvent-free conditions gave high conversion and yields, shortened reaction time, and minimized degradation products. N-Vinyloxazolidin-2-one and its analogues used in these cycloaddition reactions were conveniently prepared in excellent yields by a modified version of Buchwald's one-step copper-catalyzed vinylation using vinyl bromide. From the adducts, a two-step access to various unsymmetric aspartate derivatives was also described.