1018818-04-6 Usage
General Description
"(2R,4S)-1-Boc-4-Methylpyrrolidine-2-carboxylic acid" is a chemical compound with a molecular formula of C12H21NO4. It is a derivative of pyrrolidine and is commonly used as a building block in organic synthesis. The compound is a white solid at room temperature and is primarily used in the pharmaceutical industry for the production of various drugs and pharmaceutical intermediates. It is a chiral compound, meaning it has a non-superimposable mirror image, and its specific stereochemistry is important for its biological activity. The compound is also known by its systematic name N-[(2R,4S)-4-Methyl-2-pyrrolidinyl]-2-methylpropanamide and is often referred to by its abbreviation, (R,S)-Boc-4-Me-Proline.
Check Digit Verification of cas no
The CAS Registry Mumber 1018818-04-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,1,8,8,1 and 8 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1018818-04:
(9*1)+(8*0)+(7*1)+(6*8)+(5*8)+(4*1)+(3*8)+(2*0)+(1*4)=136
136 % 10 = 6
So 1018818-04-6 is a valid CAS Registry Number.
1018818-04-6Relevant articles and documents
Total synthesis, NMR solution structure, and binding model of the potent histone deacetylase inhibitor FR235222
Rodriquez, Manuela,Terracciano, Stefania,Cini, Elena,Settembrini, Giulia,Bruno, Ines,Bifulco, Giuseppe,Taddei, Maurizio,Gomez-Paloma, Luigi
, p. 423 - 427 (2007/10/03)
An alternative route: The fungal metabolite FR235222, a potent inhibitor of mammalian histone deacetylase (HDAC), has been synthesized. Key steps are the preparation of unusual amino acids Ahoda and (2R,4S)-MePro. A 3D model for cyclopeptide inhibitor int