1018909-64-2Relevant academic research and scientific papers
Analogues of 2-aminopyridine-based selective inhibitors of neuronal nitric oxide synthase with increased bioavailability
Lawton, Graham R.,Ranaivo, Hantamalala Ralay,Chico, Laura K.,Ji, Haitao,Xue, Fengtian,Martasek, Pavel,Roman, Linda J.,Martin Watterson,Silverman, Richard B.
, p. 2371 - 2380 (2009)
Overproduction of nitric oxide by neuronal nitric oxide synthase (nNOS) has been linked to several neurodegenerative diseases. We have recently designed potent and isoform selective inhibitors of nNOS, but the lead compound contains several basic function
POTENT AND HIGHLY SELECTIVE HETEROAROMATIC INHIBITORS OF NEURONAL NITRIC OXIDE SYNTHASE
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Page/Page column 51; 52, (2008/06/13)
Peptidomimetic compounds as can inhibit neuronal nitric oxide synthase (nNOS) for potential treatment in neurodegenerative diseases, such as but not limited to stroke, Alzheimer's disease, Parkinson's disease, Huntington's disease.
