101908-83-2

Upstream product

• 100-39-0 benzyl bromide 
• 101908-82-1 2-bromo-5-methylbenzene-1,3-diol 
• 504-15-4 orcinol 
• 4179-19-5 1,3-dimethoxy-5-methylbenzene 
• 2675-82-3 bromo-4-dimethoxy-3,5-toluene 

Downstream Products

• 101923-78-8 C₅₉H₅₈O₁₁ 
• 101909-25-5 dihydroxy-3,8-(dimethoxy-2,4-methoxycarbonyl-5-dimethyl-3,6-benzyl)-9-trimethyl-1,4,6-oxo-11-11H-dibenzodioxepinne<1,4>carboxylate-7 de methyle 
• 101923-77-7 dihydroxy-2,4-(dihydroxy-2,4-dimethyl-3,6-benzoyl)-5-(dimethoxy-2,4-methoxycarbonyl-5-dimethyl-3,6-benzyl)-3-benzoate de methyle 
• 101923-79-9 dihydroxy-4',6-(dimethoxy-2,4-methoxycarbonyl-5-dimethyl-3,6-benzyl)-3'-methoxycarbonyl-5'-trimethyl-4,6',7-spirodione-2',3 
• 101909-17-5 (formyl-3-dihydroxy-2,6-methyl-4-benzyl)-3-dimethoxy-4,6-dimethyl-2,5-benzoate de methyle 
• 101909-16-4 (dibenzyloxy-2,6-methyl-4-benzyl)-3-dimethoxy-4,6-dimethyl-2,5-benzoate de methyle 

Relevant academic research and scientific papers

205. Synthese d'une nouvelle depsidone derivee de l'acide furfurique, le dimethoxy-3,8-(dimethoxy-2,4-methoxycarbonyl-5-dimethyl-3,6-benzyl)-9-trimethyl-1,4,6-oxo-11-11H-dibenzodioxepinnecarboxylate-7 de methyle

The total synthesis of the title compound 1b is described.Starting from simple orcinol and β-orcinol units, the benzophenone 4 has been prepared.Using a biomimetic reaction, the intramolecular oxydative coupling, lead to the grisadienedione 25.By thermal interconversion and permethylation, the depsidone 1b has been obtained.

Facile and divergent optimization of chromazonarol enabled the identification of simplified drimane meroterpenoids as novel pharmaceutical leads

The diversity of drimane hydroquinones was significantly expanded by the facile construction of (+)-chromazonarol relevant natural products, isomers, and analogues for the discovery of new pharmaceutical leads. The structure-activity relationship of (+)-c