10195-68-3

Usage

Uses

Used in Scientific Experiments:
Benzenesulfonyl semicarbazide is used as a reagent in various scientific experiments for its ability to participate in chemical reactions, making it a valuable component in research settings.
Used in Industrial Processes:
In industrial applications, Benzenesulfonyl semicarbazide is used as an intermediate in the synthesis of other organic compounds, contributing to the production of various chemical products.
Used in Pharmaceutical Synthesis:
Benzenesulfonyl semicarbazide is used as a key component in the synthesis of certain medicines, leveraging its reactivity to facilitate the creation of pharmaceutical compounds. This makes it an essential part of the drug development process in the pharmaceutical industry.

Upstream product

• 123-77-3 Azodicarboxamid 
• 873-55-2 sodium benzenesulfonate 
• 4426-72-6 hydrazine carboxamide 
• 98-09-9 benzenesulfonyl chloride 

Downstream Products

• 60226-41-7 C₁₂H₁₇N₃O₅S 
• 60226-40-6 C₁₁H₁₅N₃O₅S 
• 60226-42-8 C₁₂H₁₇N₃O₅S 

Relevant academic research and scientific papers

An efficient synthesis of sulfonylhydrazides and sulfonylsemicarbazides by utilizing alumina as a catalyst

Sulfonyl hydrazides and sulfonyl semicarbazides are readily prepared by the reacting of hydrazine derivatives with sulfonyl chlorides in the presence of basic alumina under solvent-free conditions. Reaction of a sulfonyl chloride with t-butylcarbazate, followed by hydrolysis provides the corresponding sulfonyl hydrazides in higher yield and shorter time than previously reported.

A convenient procedure for the preparation of sulfonamidoureas using triphosgene

An efficient method for the preparation of sulfonamidourea using triphosgene in organic solvents is reported. Sulfonylhydrazides and acetylsulfanilylhydrazide were transformed into the corresponding intermediates using triphosgene in 1,4-dioxane/water or tetrahydrofuran as solvents. These intermediates were converted in situ into symmetrical and unsymmetrical sulfonamidoureas in high yields and shorter periods of time related to previous methods.