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1019637-75-2

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1019637-75-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1019637-75-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,1,9,6,3 and 7 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1019637-75:
(9*1)+(8*0)+(7*1)+(6*9)+(5*6)+(4*3)+(3*7)+(2*7)+(1*5)=152
152 % 10 = 2
So 1019637-75-2 is a valid CAS Registry Number.

1019637-75-2Downstream Products

1019637-75-2Relevant articles and documents

Design and synthesis of DPP-IV inhibitors lacking the electrophilic nitrile group

Kondo, Takashi,Nekado, Takahiro,Sugimoto, Isamu,Ochi, Kenya,Takai, Shigeyuki,Kinoshita, Atsushi,Hatayama, Akira,Yamamoto, Susumu,Kishikawa, Katsuya,Nakai, Hisao,Toda, Masaaki

, p. 1613 - 1631 (2008/09/20)

A series of (4β-substituted)-l-prolylpyrrolidine analogs lacking the electrophilic nitrile function were synthesized and their dipeptidyl peptidase IV (DPP-IV) inhibitory activity and duration of ex vivo activity were evaluated. Structural optimization of a N-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine analog 8, which was found by high-speed analog synthesis, was carried out to improve the potency and duration of action. A representative compound 26 was evaluated to assess its effect on the plasma glucose level after the oGTT (oral glucose tolerance test) in normal rats. Structure-activity relationships (SAR) are also presented.

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