1019654-18-2Relevant academic research and scientific papers
SN2″-Selective and Enantioselective Substitution with Unsaturated Organoboron Compounds and Catalyzed by a Sulfonate-Containing NHC-Cu Complex
Zhou, Yuebiao,Shi, Ying,Torker, Sebastian,Hoveyda, Amir H.
supporting information, p. 16842 - 16854 (2018/11/27)
The first broadly applicable strategy for SN2″-selective and enantioselective catalytic substitution is disclosed. Transformations are promoted by 5.0 mol% of a sulfonate-containing NHC-Cu complex (NHC = N-heterocyclic carbene), and are carried
N,N,N′,N′-Tetramethylenediamine dioxide (TMEDAO2) facilitates atom economical/open atmosphere Ley-Griffith (TPAP) tandem oxidation-Wittig reactions
Read, Christopher D. G.,Moore, Peter W.,Williams, Craig M.
, p. 4537 - 4540 (2015/09/15)
N,N,N′,N′-Tetramethylethylenediamine dioxide (TMEDAO2) was explored as a more atom economical co-oxidant for the Ley-Griffith oxidation of alcohols to aldehydes. TMEDAO2 was found to selectivity oxidise benzylic and allylic alcohols in comparable yields to that of the standard Ley-Griffith co-oxidant (NMO). Importantly TMEDAO2 facilitated tandem Ley-Griffith-Wittig reactions with stabilised ylides, in good to excellent yields, without the requirement of anhydrous conditions.
New potent and selective polyfluoroalkyl ketone inhibitors of GVIA calcium-independent phospholipase A2
Magrioti, Victoria,Nikolaou, Aikaterini,Smyrniotou, Annetta,Shah, Ishita,Constantinou-Kokotou, Violetta,Dennis, Edward A.,Kokotos, George
supporting information, p. 5823 - 5829 (2013/09/12)
Group VIA calcium-independent phospholipase A2 (GVIA iPLA 2) has recently emerged as an important pharmaceutical target. Selective and potent GVIA iPLA2 inhibitors can be used to study its role in various neurological diso
