101986-32-7

Basic information

• Product Name: 3-Oxazolidineacetonitrile, 4-phenyl-, (R)-
• CAS NO: 101986-32-7
• Molecular Formula: C11H12N2O
• Molecular Weight: 188.229
• Mol File: 101986-32-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-Oxazolidineacetonitrile, 4-phenyl-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Oxazolidineacetonitrile, 4-phenyl-, (R)-(101986-32-7)
• EPA Substance Registry System: 3-Oxazolidineacetonitrile, 4-phenyl-, (R)-(101986-32-7)

Safety Data

• Hazardous Substances Data: 101986-32-7(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 111980-33-7 (-)-N-cyanomethylphenylglycinol 
• 56613-80-0 D-2-phenylglycinol 
• 151-50-8 potassium cyanide 

Downstream Products

• 127196-23-0 (1R,3aR,6aS)-4,6-Dioxo-5-phenyl-2-((R)-1-phenyl-2-trimethylsilanyloxy-ethyl)-octahydro-pyrrolo[3,4-c]pyrrole-1-carbonitrile 
• 127253-91-2 (1S,3aS,6aR)-4,6-Dioxo-5-phenyl-2-((R)-1-phenyl-2-trimethylsilanyloxy-ethyl)-octahydro-pyrrolo[3,4-c]pyrrole-1-carbonitrile 
• 127196-23-0 4,6-Dioxo-5-phenyl-2-((R)-1-phenyl-2-trimethylsilanyloxy-ethyl)-octahydro-pyrrolo[3,4-c]pyrrole-1-carbonitrile 
• 127253-92-3 (1S,3aR,6aS)-4,6-Dioxo-5-phenyl-2-((R)-1-phenyl-2-trimethylsilanyloxy-ethyl)-octahydro-pyrrolo[3,4-c]pyrrole-1-carbonitrile 
• 127253-93-4 (1R,3aS,6aR)-4,6-Dioxo-5-phenyl-2-((R)-1-phenyl-2-trimethylsilanyloxy-ethyl)-octahydro-pyrrolo[3,4-c]pyrrole-1-carbonitrile 
• 101986-33-8 N-(1-cyanoethyl)-4-phenyl-1,3-oxazolidine 
• 114498-09-8 (1S,2R)-2-Hydroxymethyl-1-((R)-2-hydroxy-1-phenyl-ethylamino)-cyclopropanecarboxylic acid methyl ester 
• 119066-47-6 (1R,2S)-2-Hydroxymethyl-1-((R)-2-hydroxy-1-phenyl-ethylamino)-cyclopropanecarboxylic acid methyl ester 
• 119068-17-6 (1S,5S)-1-((R)-2-Hydroxy-1-phenyl-ethylamino)-3-oxa-bicyclo[3.1.0]hexan-2-one 
• 119068-14-3 (1R,5R)-1-((R)-2-Hydroxy-1-phenyl-ethylamino)-3-oxa-bicyclo[3.1.0]hexan-2-one 
• 118970-47-1 2-Hydroxymethyl-1-((R)-4-phenyl-oxazolidin-3-yl)-cyclopropanecarbonitrile 
• 125830-46-8 (1R,3S,5R)-1-Hydroxymethyl-5-phenyl-7-oxa-4-aza-spiro[2.5]octan-8-one 
• 125876-10-0 (1S,3R,5R)-1-Hydroxymethyl-5-phenyl-7-oxa-4-aza-spiro[2.5]octan-8-one 
• 103539-09-9 (3S,5R)-3-Hexyl-2-methyl-5-phenyl-morpholin-2-ol 

Relevant articles and documents

Synthesis of morpholin-2-ones by chemoselective intramolecular rhodium-catalyzed reductive ring expansion of oxazolidines

(Chemical Equation Presented) The rhodium-catalyzed reductive intramolecular ring expansion of N-(ethoxycarboxymethyl)oxazolidines was carried out under an atmosphere of carbon monoxide and hydrogen to afford N-methylmorpholin-2-ones in good to excellent

aSYMMETRIC SYNTHESIS IV1. PRAPARATION OF CHIRAL α-AMINONITRILES FROM A NEW N-CYANOMETHYL-1,3-OXAZOLIDINE SYNTHON

The synthesis of (-)-N-cyanomethyl-4-phenyl-1,3-oxazolidine 1 is reported.Good yields and moderate diastereomeric excesses (d.e.s.) of mono- and di-substituted α-aminonitriles were obtained from simple chiral template.