1019877-80-5

Basic information

• Product Name: 1-[(2,2-dimethyl-1,3-dioxolan-4-yl)methyl]-3-(4-fluorophenyl)-4-(pyridin-4-yl)quinolin-2(1H)-one
• Synonyms: 1-[(2,2-dimethyl-1,3-dioxolan-4-yl)methyl]-3-(4-fluorophenyl)-4-(pyridin-4-yl)quinolin-2(1H)-one
• CAS NO: 1019877-80-5
• Molecular Weight: 430.479
• Mol File: 1019877-80-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[(2,2-dimethyl-1,3-dioxolan-4-yl)methyl]-3-(4-fluorophenyl)-4-(pyridin-4-yl)quinolin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(2,2-dimethyl-1,3-dioxolan-4-yl)methyl]-3-(4-fluorophenyl)-4-(pyridin-4-yl)quinolin-2(1H)-one(1019877-80-5)
• EPA Substance Registry System: 1-[(2,2-dimethyl-1,3-dioxolan-4-yl)methyl]-3-(4-fluorophenyl)-4-(pyridin-4-yl)quinolin-2(1H)-one(1019877-80-5)

Safety Data

• Hazardous Substances Data: 1019877-80-5(Hazardous Substances Data)

Upstream product

• 36236-76-7 4-(bromomethyl)-2,2-dimethyl-1,3-dioxolane 
• 917460-80-1 3-(4-fluorophenyl)-4-pyridin-4-ylquinoline-2(1H)-one 

Downstream Products

• 1019877-92-9 1-(2,3-dihydroxypropyl)-3-(4-fluorophenyl)-4-(pyridin-4-yl)quinolin-2-(1H)-one 

Relevant articles and documents

Implications for selectivity of 3,4-diarylquinolinones as p38αMAP kinase inhibitors

In this study we report on the specificity profiling of the MAP kinase inhibitors 1, 2, and 3 in a panel of 78 protein kinases including the MAPK isoforms p38(α,β,γ,δ), JNK1/2/3, and ERK1/2/8 showing 3-(4-fluorophenyl)-4-pyridin-4-ylquinolin-2(1H)-one (1)