102-17-0Relevant articles and documents
Palladium-catalyzed carbonylation of benzylic ammonium salts to amides and esters: Via C-N bond activation
Yu, Weijie,Yang, Shuwu,Xiong, Fei,Fan, Tianxiang,Feng, Yan,Huang, Yuanyuan,Fu, Junkai,Wang, Tao
supporting information, p. 3099 - 3103 (2018/05/22)
An efficient palladium-catalyzed carbonylation reaction of readily available quaternary ammonium salts with CO is reported for the first time to afford arylacetamides and arylacetic acid esters via benzylic C-N bond cleavage. This protocol features mild reaction conditions under atmospheric pressure of CO, a redox-neutral process without an additional oxidant, and a broad substrate scope for various kinds of amines, alcohols and phenols.
A convenient preparation of p-methoxybenzyl esters
Wang,Golding,Potter
, p. 4197 - 4204 (2007/10/03)
Carboxylic acids are conveniently and efficiently protected as their p-methoxybenzyl esters under very mild conditions using the pre-formed reagent N,N'-diisopropyl-O-(4-methoxybenzyl)isourea, and this method allows selective protection of carboxylic acids in the presence of other functionalities such as enolisable ketones and alcohol groups.
Synthesis of substituted benzyl esters
-
, (2008/06/13)
A process for preparing certain substituted benzyl esters of phenylacetic acids by esterification in a solvent in which the salt of the acid is insoluble, and in the presence of a phase transfer catalyst.