1020-67-3Relevant articles and documents
A new copper-based metal-organic framework as a promising heterogeneous catalyst for chemo- and regio-selective enamination of β-ketoesters
Zhao, Ying,Deng, Dong-Sheng,Ma, Lu-Fang,Ji, Bao-Ming,Wang, Li-Ya
, p. 10299 - 10301 (2013)
Assembly of 5-nitro-1,2,3-benzenetricarboxylic acid (H3nbta) with CuII in the presence of 1,3-bis(1,2,4-triazol-1-yl)propane (1,3-btp) leads to a new metal-organic framework, [Cu(Hnbta)(1,3-btp)] ·2H2O (A1), which is shown to be an efficient and recyclable heterogeneous catalyst for enamination of β-ketoesters with excellent product yields and selectivity.
Cerium(III) chloride heptahydrate (CeCl3·7H2O) as an efficient enamination catalyst in aqueous media
Khodaei,Khosropour,Kookhazadeh
, p. 1445 - 1448 (2005)
Cerium(III) chloride heptahydrate CeCl3·H2O catalyzes enamination of β-dicarbonyl compounds with primary amines in aqueous medium at room temperature to afford the corresponding β-enamino ketones with high chemoselectivity.
Iodine-Promoted Construction of Polysubstituted 2,3-Dihydropyrroles from Chalcones and β-Enamine Ketones (Esters)
Li, Yujin,Xu, Hui,Xing, Mengming,Huang, Fang,Jia, Jianhong,Gao, Jianrong
, p. 3690 - 3693 (2015)
A novel approach for the synthesis of a variety of polysubstituted trans-2,3-dihydropyrroles from a wide range of chalcones and β-enamine ketones (esters) via iodine-promoted tandem Michael/cyclization sequence has been developed, affording the desired products in moderate to excellent yields. This methodology is a highly efficient, convenient way to access functionalized 2,3-dihydropyrroles from readily accessible substrates under mild reaction conditions.
Synthesis, spectral and structural characterization of cobalt(III) dithiocarbamato complexes: Catalytic application for the solvent free enamination reaction
Bharati, Pooja,Bharti,Nath,Bharty,Butcher,Singh
, p. 375 - 385 (2015)
The syntheses, spectral, structural and catalytic properties of some new cobalt(III) complexes, [Co(mpcdt)3] (1), [Co(ppcdt)3] (2) and [Co(mppcdt)3]·0.25CHCl3 (3), derived from 4-methyl piperazine-1-carbodithioate (mpcdt), 4-phenyl piperazine-1-carbodithioate (ppcdt) and 4-(2-methoxyphenyl) piperazine-1-carbodithioate (mppcdt) have been described. A series of β-enaminoesters and β-enaminones were obtained in about 90% yield by the reactions of β-ketoesters and 1,3-diketones with aliphatic and aromatic amines using 1-2 mol% of the above cobalt(III) complexes as catalysts and these have been characterized by NMR, GC-MS and X-ray crystallography. Complexes 1, 2 and 3 are stabilized by intermolecular C-H?S interactions, leading to the formation of supramolecular architectures. Thermogravimetric analysis of complexes 1 and 2 have been investigated by TG-DTA, which indicate that cobalt sulfide is formed as the final product.
Solvent-free and efficient synthesis of highly functionalized cyclohexa-1,3-diene derivatives via a novel one-pot three-component reaction
Alizadeh, Abdolali,Rezvanian, Atieh,Mokhtari, Javad
, p. 3491 - 3495 (2011)
A catalyst-free and convenient approach for the preparation of cyclohexa-1,3-dienecarboxylate derivatives is described. This three-component reaction between primary amines, alkyl acetoacetate, and dibenzylideneacetone proceeds under solvent-free condition in good to excellent yields. Georg Thieme Verlag Stuttgart.
Photocatalytic Visible-Light-Induced Nitrogen Insertion via Dual C(sp3)-H and C(sp2)-H Bond Functionalization: Access to Privileged Imidazole-based Scaffolds
Patel, Srilaxmi M.,P., Ermiya Prasad,Bakthadoss, Manickam,Sharada, Duddu S.
supporting information, p. 257 - 261 (2021/01/15)
Here we have demonstrated a visible-light-mediated metal-free organic-dye-catalyzed dehydrogenative N-insertion leading to highly substituted imidazoles and privileged dihydroisoquinoline-based imidazole derivatives via C(sp3)-H and C(sp2)-H bond functionalization. A sustainable, convenient, metal-free azidation/C-H aminative cyclization approach in the absence of stoichiometric oxidants is presented. This protocol involves a rare photoinduced iminyl radical as a key intermediate for the "N"insertion.
Nenitzescu Synthesis of 5-Hydroxyindoles with Zinc, Iron and Magnesium Salts in Cyclopentyl Methyl Ether
Azzena, Ugo,Beccu, Andrea,Carboni, Silvia,Carraro, Massimo,De Luca, Lidia,Gaspa, Silvia,Livesi, Marco,Pira, Giovanni Michele,Pisano, Luisa,R?mer, Melina,Satta, Giuseppe,Solinas, Angelo,Usala, Elena
supporting information, p. 5835 - 5842 (2021/11/17)
In this work, mild Lewis acids and low environmental impact solvents were investigated for Nenitzescu synthesis. Cyclopentyl methyl ether can be used at room temperature in substitution of halogenated solvents with zinc, iron and magnesium salts as homogeneous catalysts to give 5-hydroxyindoles in fair to good yields. The reaction features a straightforward workup and excellent solvent recycle.
