6335-80-4

Basic information

• Product Name: ETHYL3-(BENZYLAMINO)BUTANOATE
• Synonyms: Butanoic acid, 3-[(phenylmethyl)amino]-, ethyl ester
• CAS NO: 6335-80-4
• Molecular Formula: C₁₃H₁₉NO₂
• Molecular Weight: 221.3
• Mol File: 6335-80-4.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 317.4°C at 760 mmHg
• Flash Point: 145.7°C
• Appearance: /
• Density: 1.017g/cm³
• Vapor Pressure: 0.000386mmHg at 25°C
• Refractive Index: 1.503
• PKA: 8.65±0.19(Predicted)
• CAS DataBase Reference: ETHYL3-(BENZYLAMINO)BUTANOATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL3-(BENZYLAMINO)BUTANOATE(6335-80-4)
• EPA Substance Registry System: ETHYL3-(BENZYLAMINO)BUTANOATE(6335-80-4)

Safety Data

• Hazardous Substances Data: 6335-80-4(Hazardous Substances Data)

Usage

General Description

ETHYL3-(BENZYLAMINO)BUTANOATE is a chemical compound with the molecular formula C13H19NO2. It is an ester, which means that it is formed from the reaction between an alcohol and an acid. ETHYL3-(BENZYLAMINO)BUTANOATE is commonly used in the manufacturing of various products, including pharmaceuticals, perfumes, and flavorings, due to its pleasant fruity and floral aroma. It is also known for its potential use as a precursor in organic synthesis and as a building block in the preparation of other organic compounds. However, like all chemicals, ETHYL3-(BENZYLAMINO)BUTANOATE should be handled with care and in accordance with proper safety protocols to avoid any potential hazards.

InChI:InChI=1/C13H19NO2/c1-3-16-13(15)9-11(2)14-10-12-7-5-4-6-8-12/h4-8,11,14H,3,9-10H2,1-2H3

Upstream product

• 623-70-1 ethyl (E)-crotonate 
• 100-46-9 benzylamine 
• 141-97-9 ethyl acetoacetate 
• 5303-65-1 3-aminobutanoic acid ethyl ester 
• 100-52-7 benzaldehyde 
• 10544-63-5 ethyl crotonate 
• 6776-19-8 ethyl (Z)-crotonate 
• 21759-74-0 ethyl (Z)-3-(benzylamino)-2-butenoate 
• 1020-67-3 ethyl 3-(benzylamino)crotonate 

Downstream Products

• 1258723-55-5 1-benzyl-2,5-dimethyl-6-oxo-1,2,3,6-tetrahydropyridin-4-yl trifluoromethanesulfonate 
• 6938-07-4 N,N-bis(2-ethoxycarbonylethyl)benzylamine 
• 58859-66-8 N-(carbethoxy-2 ethyl) benzylamino-3 butyrate d'ethyle 
• 116140-33-1 N-carbethoxy-2-methyl-5-carbethoxy-4-piperidone 
• 98014-59-6 Benzyl-(3-hydroxy-1-methyl-propyl)-carbamic acid tert-butyl ester 
• 98014-60-9 tert-butyl N-benzyl-N-(1-methyl-3-oxopropyl)carbamate 
• 4391-83-7 1-benzyl-4-methylazetidinone 
• 5303-65-1 3-aminobutanoic acid ethyl ester 
• 121006-14-2 3-(Benzylamino)-1-butanol 
• 91246-78-5 3-benzylaminobutyric acid 
• 321345-30-6 ⁽¹⁾-4-amino-1-benzyl-2-methylpiperidine 
• 203661-73-8 (+/-)-1-benzyl-2-methylpiperidine-4-one 
• 1172607-95-2 (R)-(-)-N-benzyl-3-(benzylamino)butanamide 

Relevant articles and documents

Development of a continuously operating process for the enantioselective synthesis of a b-amino acid ester via a solvent-free chemoenzymatic reaction sequence

A sequential, chemoenzymatic process for a continuously operating production of the chiral β-amino acid ester ethyl (S)-3-(benzylamino)- butanoate was developed. The reactor set-up combined a plug-flow reactor for the thermal aza-Michael addition of benzy

KRAS G12C Mutant protein inhibitors

The invention discloses compounds which irreversibly inhibit KRAS G12C mutation. A pharmaceutically acceptable salt and of the compound contains the compound or a salt thereof, and the invention also discloses an application of the compound or a salt and of the compound in the treatment KRAS G12C of a proliferative disease such as a sudden tumor.

A piperidine compound and method for preparing the same

The invention relates to a piperidine compound and a preparation method thereof. The compound is 2-methyl-4-N-tert-butyloxycarboryl piperidine. The preparation method comprises the following steps of (1) adding a compound (1) ethyl crotonate and benzylami