102008-18-4 Usage
Chemical compound
2-(1-phenyl-3-piperidino-propyl)-pyridine is a chemical compound with a molecular formula of C21H25N.
Psychoactive drug
It is a psychoactive drug that acts as a selective sigma receptor agonist.
Potential use
PAPP has been studied for its potential use in the treatment of neurodegenerative disorders, particularly Alzheimer's disease, and as an antidepressant.
Cognitive enhancer
It has also been investigated for its potential as a cognitive enhancer.
Neurotransmitter modulation
PAPP's pharmacological effects are thought to be related to its ability to modulate the release of neurotransmitters such as dopamine and serotonin.
Preclinical studies
It has shown promise in preclinical studies for its potential in treating various neurological and psychiatric conditions.
Further research needed
Further research is needed to fully understand PAPP's therapeutic potential and safety profile.
Check Digit Verification of cas no
The CAS Registry Mumber 102008-18-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,2,0,0 and 8 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 102008-18:
(8*1)+(7*0)+(6*2)+(5*0)+(4*0)+(3*8)+(2*1)+(1*8)=54
54 % 10 = 4
So 102008-18-4 is a valid CAS Registry Number.
102008-18-4Relevant articles and documents
Hydroaminomethylation with novel Rhodium-Carbene complexes: An efficient catalytic approach to pharmaceuticals
Ahmed, Moballigh,Buch, Cathleen,Routaboul, Lucie,Jackstell, Ralf,Klein, Holger,Spannenberg, Anke,Beller, Matthias
, p. 1594 - 1601 (2008/02/04)
Starting from [{Rh(cod)Cl}2] and 1,3-dimesitylimidazole-2- ylidenes the novel [RhCl(cod)(carbene)] complexes 1-5 have been synthesized, characterized, and tested in the hydroaminomethylation of aromatic olefins. The influence of different ligands and reaction parameters on the catalytic activity was investigated in detail applying 1,1-diphenylethylene and piperidine as a model system. The scope and limitations of the novel catalysts is shown in the preparation of 16 biologically active 1-amino-3,3-diarylpropenes. In general, high chemo- and regioselectivity as well as good yields of the desired products were achieved.
