102008-33-3Relevant academic research and scientific papers
One-step three-component coupling of aromatic organozinc reagents, secondary amines, and aromatic aldehydes into functionalized diarylmethylamines
Le Gall, Erwan,Troupel, Michel,Nédélec, Jean-Yves
, p. 9953 - 9965 (2007/10/03)
Numerous functionalized diarylmethylamines have been synthesized in high yield according to a one-step three-component coupling between an aromatic organozinc reagent, a secondary amine, and an aromatic aldehyde. Both organozinc species and aldehyde can bear a functional group and either aromatic or non-aromatic amines can be used in this versatile procedure.
