1020100-86-0

Upstream product

• 929896-96-8 4-[N-(dichloroacetyl)-N-methylamino]benzyl alcohol 
• 174497-93-9 2'-O-methylthiomethyl-3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)uridine 
• 10541-83-0 N-methyl-p-aminobenzoic acid 
• 181819-75-0 (4-(methylamino)phenyl)methanol 
• 69304-38-7 3',5'-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)uridine 
• 58-96-8 uridine 
• 69304-37-6 1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane 

Downstream Products

• 1020100-87-1 2'-O-[[[4-[N-(dichloroacetyl)-N-methylamino]benzyl]oxy]methyl]uridine 
• 1020100-92-8 5'-O-(4,4'-dimethoxytrityl)-2'-O-[[[4-[N-(dichloroacetyl)-N-methylamino]benzyl]oxy]methyl]uridine 
• 1020100-95-1 5'-O-(4,4'-dimethoxytrityl)-3'-O-[(N,N-diisopropylamino)(2-cyanoethyloxy)phosphinyl]-2'-O-[4-(N-dichloroacetyl-N-methylamino)benzyloxy]methyluridine 

Relevant academic research and scientific papers

The 4-(N-dichloroacetyl-N-methylamino)benzyloxymethyl group for 2′-hydroxyl protection of ribonucleosides in the solid-phase synthesis of oligoribonucleotides

(Chemical Equation Presented) Emerging RNA-based technologies for controlling gene expression have triggered a high demand for synthetic oligoribonucleotides and have motivated the development of ribonucleoside phosphoramidites that would exhibit coupling

Assessment of 4-nitrogenated benzyloxymethyl groups for 2′-Hydroxyl protection in solid-phase RNA synthesis

The search for a 2′-OH protecting group that would impart ribonucleoside phosphoramidites with coupling kinetics and coupling efficiencies comparable to those of deoxyribonucleoside phosphoramidites led to an assessment of 2′-0-(4-nitrogenated benzyloxy)m