102016-76-2

Basic information

• Product Name: N-(2-(5-methoxy-1H-indol-3-yl)ethyl)-4-methylbenzenesulfonamide
• Synonyms: N-(2-(5-methoxy-1H-indol-3-yl)ethyl)-4-methylbenzenesulfonamide
• CAS NO: 102016-76-2
• Molecular Weight: 344.434
• Mol File: 102016-76-2.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: N-(2-(5-methoxy-1H-indol-3-yl)ethyl)-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-(5-methoxy-1H-indol-3-yl)ethyl)-4-methylbenzenesulfonamide(102016-76-2)
• EPA Substance Registry System: N-(2-(5-methoxy-1H-indol-3-yl)ethyl)-4-methylbenzenesulfonamide(102016-76-2)

Safety Data

• Hazardous Substances Data: 102016-76-2(Hazardous Substances Data)

Upstream product

• 608-07-1 2-(5-methoxyindol-3-yl)ethylamine 
• 98-59-9 p-toluenesulfonyl chloride 
• 66-83-1 5-methoxytryptamine hydrochloride 
• 250672-50-5 1-(tert-butyldimethylsilyl)-3-bromo-5-methoxy-1H-indole 
• 162710-95-4 1-(tert-Butyldimethylsilyl)-5-methoxyindole 
• 1006-94-6 5-methoxylindole 
• 335451-49-5 1-(tert-Butyldimethylsilyl)-5-methoxy-N-(4-methylbenzenesulfonyl)tryptamine 

Downstream Products

• 109396-21-6 N-[2-(5-methoxy-indol-3-yl)-ethyl]-N-methyl-toluene-4-sulfonamide 
• 1334298-37-1 N-(2-(5-methoxy-1-methyl-1H-indol-3-yl)ethyl)-4-methylbenzenesulfonamide 
• 1318072-93-3 C₂₈H₃₈N₂O₄SSi 
• 2009-03-2 5-methoxy-N-methyltryptamine 

Relevant articles and documents

The Plasmodium falciparum eIK1 kinase (PfeIK1) is central for melatonin synchronization in the human malaria parasite. Melatotosil blocks melatonin action on parasite cell cycle

Melatonin and its indoles derivatives are central in the synchronization of malaria parasites. In this research, we discovered that melatonin is unable to increase the parasitemia in the human malaria Plasmodium falciparum that lacks the kinase PfeIK1. Th

Synthesis of Carbolines via Palladium/Carboxylic Acid Joint Catalysis

The combination of a Pd(0) complex with benzoic acid converts propargylic tryptamines to the corresponding tetrahydro-β-carbolines. The method uses unprotected indoles and affords the desired products with ample functional group tolerance. Detailed modeling studies reveal a close synergy between the organic and metal catalysts, which enables sequential alkyne isomerization, indole C-H activation, and eventual C-C reductive elimination to afford the target heterocycles.

CuCl2/TBHP-mediated direct chlorooxidation of indoles

CuCl2/TBHP-mediated direct chlorooxidation of indole derivatives under simple aerobic conditions was reported, leading to facile preparations of a range of 3,3-disubstituted 3-chlorooxindoles in good yields and selectivities.