1020172-03-5

Upstream product

• 61637-11-4 (2E)-1-phenyl-3-[4-(trifluoromethyl)phenyl]prop-2-en-1-one 
• 98-80-6 phenylboronic acid 
• 128796-39-4 4-trifluoromethylphenylboronic acid 
• 614-47-1 1,3-diphenyl-propen-3-one 
• 61637-11-4 3-(4-(trifluoromethyl)phenyl)-1-phenylprop-2-en-1-one 
• 128796-45-2 2,4,6-tris-(4-trifluoromethylphenyl)boroxine 
• 3262-89-3 triphenylboroxine 
• 1083-30-3 dihydrochalcone 
• 402-43-7 p-trifluoromethylphenyl bromide 
• 591-50-4 iodobenzene 
• 23665-09-0 phenylzinc iodide 

Relevant academic research and scientific papers

Enantioselective Conjugate Addition of Stabilized Arylzinc Iodide to Enones: an Improved Protocol of the Hayashi Reaction

Stabilised arylzinc iodide, prepared by direct insertion of zinc into aryl iodides, were used as nucleophiles in the Hayashi Rh-catalysed enantioselective conjugate addition to enones. The reaction conditions were optimized in the addition of phenylzinc i

Enantioselective β-C(sp3)-H arylation of amides: Via synergistic nickel and photoredox catalysis

An enantioselective benzylic β-C(sp3)-H arylation of amides via synergistic nickel and photoredox catalysis is reported. The C-H bond is activated by a bromine-radical-mediated C-H cleavage. This mild yet straightforward protocol provides arylation products in up to 96% yield and with up to 95% ee. This journal is

Asymmetric Conjugate Addition of Organoboron Reagents to Common Enones Using Copper Catalysts

Copper complexes of phosphoramidites efficiently catalyzed asymmetric addition of arylboron reagents to acyclic enones. Importantly, rare 1,4-insertion of arylcopper(I) was identified which led directly to O-bound copper enolates. The new mechanism is fundamentally different from classical oxidative addition/reductive elimination of organocopper(I) on enones.

Evaluation of palladacycles as a non-rhodium based alternative for the asymmetric conjugate 1,4-addition of arylboronic acids to α,β -unsaturated enones

The asymmetric conjugate 1,4-addition of arylboronic acids to α,β-unsaturated carbonyl compounds is an extremely versatile and widely used organic transformation. While the rhodium(I)-catalysed reaction has been thoroughly explored, the asymmetric palladi

Rh/chiral sulfinylphosphine catalyzed asymmetric 1,4-addition of arylboronic acids to chalcones

A general method to obtain enantioenriched 1,3,3-triarylpropan-1-ones bearing a diarylmethine stereocenter was developed using Rh/chiral sulfinylphosphine catalyzed 1,4-addition of arylboronic acids to chalcones. The catalysis progressed smoothly in the p

A first high enantiocontrol of an asymmetric tertiary carbon center attached with a fluoroalkyl group via Rh(I)-catalyzed conjugate addition reaction

Treatment of fluoroalkylated electron-deficient olefins with various boronic acids in the presence of a catalytic amount of Rh(I) coordinated with (S)-BINAP in toluene/H2O at the reflux temperature for 3 h gave the corresponding conjugate addit