1020255-13-3Relevant academic research and scientific papers
Synthesis of arylallenes by palladium-catalyzed retro-propargylation of homopropargyl alcohols
Hayashi, Sayuri,Hirano, Koji,Yorimitsu, Hideki,Oshima, Koichiro
, p. 5048 - 5049 (2008/10/09)
Treatment of tertiary homopropargyl alcohol with aryl halide under palladium catalysis provided arylallenes regioselectively. The reaction includes retro-propargylation, which proceeds in a concerted fashion via a cyclic transition state and transfers the stereochemistry of homopropargyl alcohols through C-C bond cleavage. The present method enables the use of homopropargyl alcohols as allenylmetal equivalents. Copyright
