1020325-30-7

Basic information

• Product Name: Pyridine, 2-[3-(chloroMethyl)phenoxy]-5-(trifluoroMethyl)-
• Synonyms: Pyridine, 2-[3-(chloroMethyl)phenoxy]-5-(trifluoroMethyl)-;2-[3-(chIoromethyl)phenoxy]-5-(trifluoromethyl)pyridine;2-(3-(Chloromethyl)phenoxy)-5-(trifluoromethyl)pyridine
• CAS NO: 1020325-30-7
• Molecular Formula: C₁₃H₉ClF₃NO
• Molecular Weight: 287.6648696
• Mol File: 1020325-30-7.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Pyridine, 2-[3-(chloroMethyl)phenoxy]-5-(trifluoroMethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 2-[3-(chloroMethyl)phenoxy]-5-(trifluoroMethyl)-(1020325-30-7)
• EPA Substance Registry System: Pyridine, 2-[3-(chloroMethyl)phenoxy]-5-(trifluoroMethyl)-(1020325-30-7)

Safety Data

• Hazardous Substances Data: 1020325-30-7(Hazardous Substances Data)

Usage

General Description

Pyridine, 2-[3-(chloroMethyl)phenoxy]-5-(trifluoroMethyl)- is a chemical compound with a pyridine ring and substituents including a chloromethyl group and a trifluoromethyl group. It is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It has a variety of industrial applications, including as a solvent, a reagent in chemical reactions, and a building block for the development of new compounds. It is important to handle this chemical with care, as it can be hazardous if not used properly.

Upstream product

• 100-83-4 meta-hydroxybenzaldehyde 
• 1020333-02-1 3-((5-(trifluoromethyl)pyridin-2-yl)oxy)benzaldehyde 
• 52334-81-3 2-chloro-5-trifluoromethylpyridine 
• 620-24-6 3-Hydroxybenzyl alcohol 
• 1020325-22-7 [3-[[5-(trifluoromethyl)-2-pyridyl]oxy]phenyl]methanol 

Downstream Products

• 1020325-38-5 2-[3-(diethoxyphosphorylmethyl)phenoxy]-5-(trifluoromethyl)pyridine 
• 1020315-31-4 PF-04457845 
• 1020325-53-4 2-(3-piperidin-4-ylidenemethyl-phenoxy)-5-trifluoromethyl-pyridine hydrochloride 
• 1020325-45-4 4-[3-(5-trifluoromethyl-pyridin-2-yloxy)-benzylidene]-piperidine-1-carboxylic acid tert-butyl ester 
• 1428929-05-8 4-[[3-[[5-(trifluoromethyl)-2-pyridyl]oxy]phenyl]methylene]-cyclohexane carboxylic acid 
• 1428926-09-3 N-(5-chlorothiazol-2-yl)-4-[[3-[[5-(trifluoromethyl)-2-pyridyl]oxy]phenyl]methylene]cyclohexanecarboxamide 
• 1428926-15-1 N-[4-[[3-[[5-(trifluoromethyl)-2-pyridyl]oxy]phenyl]methylene]cyclohexyl]pyridine-3-carboxamide 
• 1428926-16-2 6-methyl-N-[4-[[3-[[5-(trifluoromethyl)-2-pyridyl]oxy]phenyl]-methylene]cyclohexyl]pyridine-3-carboxamide 
• 1428926-17-3 N-[(3E)-3-[[3-[[5-(trifluoromethyl)-2-pyridyl]oxy]phenyl]methylene]-cyclohexyl]pyrazine-2-carboxamide 
• 1428929-04-7 ethyl 4-[[3-[[5-(trifluoromethyl)-2-pyridyl]oxy]phenyl]methylene]-cyclohexane carboxylate 
• 1428929-08-1 4-[[3-[[5-(trifluoromethyl)-2-pyridyl]oxy]phenyl]methylene]-cyclohexanamine 
• 1428929-06-9 2-[3-(1,4-dioxaspiro[4.5]decan-8-ylidenemethyl)phenoxy]-5-(trifluoromethyl) pyridine 
• 1428929-07-0 4-[[3-[[5-(trifluoromethyl)-2-pyridyl]oxy]phenyl]methylene]cyclohexanone 
• 1428929-25-2 (3E)-3-[[3-[[5-(Trifluoromethyl)-2-pyridyl]oxy]phenyl]methylene]-cyclohexanamine 

Relevant articles and documents

Discovery and evaluation of novel FAAH inhibitors in neuropathic pain model

Conceptual design and modification of urea moiety in chemotype PF-3845/04457845, the bench marking irreversible inhibitor of fatty acid amide hydrolase (FAAH), led to discovery of a novel nicotinamide-based lead 12a having reversible mechanism of action.

AMIDE COMPOUNDS, COMPOSITIONS AND APPLICATIONS THEREOF

The present disclosure relates to substituted amide compounds that are inhibitors of Fatty Acid Amide Hydrolase (FAAH), their stereoisomers, tautomers, prodrugs, polymorphs, solvates, pharmaceutically acceptable salts, and pharmaceutical compositions cont

4- [3- (ARYLOXY) BENZYLIDENE] -3-METHYL PIPERIDINE ARYL CARBOXAMIDE COMPOUNDS USEFUL AS FAAH INHIBITORS

The present invention relates to compounds of Formula (I), wherein Ar is optionally substituted phenyl or heteroaryl and X, Y and Z are independently N or CH; or a pharmaceutically acceptable salt thereof; processes for the preparation of the compounds; intermediates used in the preparation of the compounds; compositions containing the compounds; and uses of the compounds in treating diseases or conditions associated with fatty acid amide hydrolase (FAAH) activity.