102067-84-5 Usage
Uses
Used in Pharmaceutical Industry:
Sappanone A is used as a potential therapeutic agent for various diseases due to its diverse biological activities. Its ability to inhibit kinase activity, such as FGFR1, KDR, c-Met, and c-Kit, makes it a promising candidate for the treatment of cancer and other related disorders.
Used in Antiviral Applications:
Sappanone A is used as an antiviral agent, particularly against influenza viruses. It inhibits the activity of influenza viral neuraminidase (NA) with low IC50 values, demonstrating its potential as a treatment for influenza infections.
Used in Antibacterial Applications:
Sappanone A is used as an antibacterial agent against both Gram-positive and Gram-negative bacteria, such as B. subtilis, B. sphaericus, S. aureus, K. aerogenes, and C. violaceum. Its broad-spectrum antimicrobial activity highlights its potential use in combating bacterial infections.
Used in Antifungal Applications:
Sappanone A is used as an antifungal agent against fungi such as A. niger and C. albicans. Its ability to inhibit fungal growth suggests its potential use in treating fungal infections.
Used in Anti-inflammatory Applications:
Sappanone A is used as an anti-inflammatory agent, as it inhibits LPS-induced inflammatory responses in vitro and in vivo. It reduces the production of nitric oxide (NO), interleukin-6 (IL-6), and prostaglandin E2 (PGE2) in RAW264.7 cells and decreases LPS-induced mortality in mice.
Used in Respiratory Disease Management:
Sappanone A is used in the management of respiratory diseases, such as asthma. It attenuates airway inflammation and mucus hypersecretion by activating the Nrf2 signaling pathway in a mouse model of ovalbumin-induced asthma, indicating its potential use in treating respiratory disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 102067-84-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,2,0,6 and 7 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 102067-84:
(8*1)+(7*0)+(6*2)+(5*0)+(4*6)+(3*7)+(2*8)+(1*4)=85
85 % 10 = 5
So 102067-84-5 is a valid CAS Registry Number.
102067-84-5Relevant academic research and scientific papers
Preparation and purification method of hematoxylone A
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, (2019/04/17)
The invention discloses a preparation and purification method of hematoxylone A, and relates to the field of pharmacy. The preparation route of the method is shown in the description. Compared with the prior art, the preparation and purification method ha
