1020673-59-9

Upstream product

• 23100-12-1 6-chloronicotinylaldehyde 
• 74572-15-9 (2S)-2-phenylmorpholine 

Downstream Products

• 1020673-22-6 (5-tert-butyl-isoxazol-3-yl)-[5-((S)-2-phenyl-morpholin-4-ylmethyl)-pyridin-2-yl]-amine 
• 1151825-97-6 C₂₅H₂₉N₃O 
• 1020673-40-8 (2,4-dichloro-phenyl)-[5-((S)-2-phenyl-morpholin-4-ylmethyl)-pyridin-2-yl]-amine 
• 1151826-05-9 C₂₈H₂₇N₃O 
• 1020673-52-2 [5-((S)-2-phenyl-morpholin-4-ylmethyl)-pyridin-2-yl]-p-tolyl-amine 
• 1020673-51-1 (4-chloro-phenyl)-[5-((S)-2-phenyl-morpholin-4-ylmethyl)-pyridin-2-yl]-amine 
• 1020673-23-7 (4-methoxy-phenyl)-[5-((S)-2-phenyl-morpholin-4-ylmethyl)-pyridin-2-yl]-amine 
• 1151826-02-6 C₂₄H₂₈N₄O 
• 1020673-47-5 (3-chloro-phenyl)-[5-((S)-2-phenyl-morpholin-4-ylmethyl)-pyridin-2-yl]-amine 
• 1020673-38-4 (2-chloro-phenyl)-[5-((S)-2-phenyl-morpholin-4-ylmethyl)-pyridin-2-yl]-amine 
• 1020673-48-6 (3,4-dichloro-phenyl)-[5-((S)-2-phenyl-morpholin-4-ylmethyl)-pyridin-2-yl]-amine 
• 1020673-50-0 (4-fluoro-phenyl)-[5-((S)-2-phenyl-morpholin-4-ylmethyl)-pyridin-2-yl]-amine 

Relevant academic research and scientific papers

Morpholine containing CB2 selective agonists

Identification and optimization of two classes of CB2 selective agonists are described. A representative from each class is profiled in a murine model of inflammation and each shows similar efficacy to prednisolone upon oral dosing.

POLYCYCLIC COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR

Compounds of formula (I) are disclosed. Compounds according to the invention are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treati