1020719-44-1 Usage
Uses
Used in Pharmaceutical Industry:
2-[2-(4-Fluorophenyl)-2-oxo-1-phenyl-D5-ethyl]-4-methyl-3-oxo-pentanoic Acid, (4-Benzyloxy-phenyl)-amide is used as an intermediate compound for the production of Atorvastin. This application is due to its role in the synthesis of the drug, which is a selective, competitive HMG-CoA reductase inhibitor. Atorvastin is specifically indicated for lowering elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia, making this intermediate compound crucial for the development and manufacturing of an effective treatment for high cholesterol levels.
Check Digit Verification of cas no
The CAS Registry Mumber 1020719-44-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,0,7,1 and 9 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1020719-44:
(9*1)+(8*0)+(7*2)+(6*0)+(5*7)+(4*1)+(3*9)+(2*4)+(1*4)=101
101 % 10 = 1
So 1020719-44-1 is a valid CAS Registry Number.
1020719-44-1Relevant academic research and scientific papers
Synthesis of deuterium-labeled atorvastatin and its metabolites for use as internal standards in a LC/MS/MS method developed for quantitation of the drug and its metabolites in human serum
Chen, Bang-Chi,Sundeen, Joseph E.,Guo, Peng,Bednarz, Mark S.,Hangeland, Jon J.,Ahmed, Syed Z.,Jemal, Mohammed
, p. 261 - 270 (2007/10/03)
D5-labeled isotopomers of atorvastatin, atorvastatin lactone and its hydroxy metabolites were synthesized as internal standards for use in a LC/MS/MS method developed for the simultaneous quantitative determination of atorvastatin and its hydroxy metabolites in human serum. d5-Atorvastatin and d5-atorvastatin lactone were prepared from d5-aniline whereas their corresponding hydroxy metabolites were synthesized using d5-benzaldehyde.
