1020719-54-3 Usage
Uses
Used in Pharmaceutical Industry:
9-[2-(HYDROXYPROPYL-D6)] ADENINE is used as a pharmaceutical compound for its potential therapeutic applications. The deuterium labeling in its structure may offer advantages in terms of stability, solubility, and bioavailability, making it a promising candidate for drug development.
Used in Research and Development:
In the field of research and development, 9-[2-(HYDROXYPROPYL-D6)] ADENINE serves as a valuable tool for studying the structure, function, and interactions of nucleic acids and their components. The deuterated nature of the compound can provide insights into the behavior of similar non-deuterated molecules, aiding in the understanding of fundamental biological processes.
Used in Diagnostic Applications:
9-[2-(HYDROXYPROPYL-D6)] ADENINE can be employed as a diagnostic agent, particularly in the detection and monitoring of diseases related to nucleic acid metabolism. The deuterium labeling may enhance the sensitivity and specificity of diagnostic assays, leading to improved accuracy in disease detection.
Used in Chemical Synthesis:
As a deuterated acyclic nucleotide, 9-[2-(HYDROXYPROPYL-D6)] ADENINE can be utilized as a starting material or intermediate in the synthesis of other deuterated nucleotide analogs and derivatives. This can be particularly useful in the development of novel therapeutic agents, imaging agents, or research tools.
Check Digit Verification of cas no
The CAS Registry Mumber 1020719-54-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,0,7,1 and 9 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1020719-54:
(9*1)+(8*0)+(7*2)+(6*0)+(5*7)+(4*1)+(3*9)+(2*5)+(1*4)=103
103 % 10 = 3
So 1020719-54-3 is a valid CAS Registry Number.
1020719-54-3Relevant academic research and scientific papers
Rivera, Nelo R.,Moore, Jeffrey,Schenk, David J.,Wang, Heather,Hesk, David,Mergelsberg, Ingrid
, p. 1090 - 1092 (2016)
Isotopically labeled compounds have numerous applications in drug discovery and development. (R)-9-(2-Hydroxypropyl)adenine 1 is an important intermediate in the synthesis of various acyclic nucleoside phosphonates including tenofovir. We have developed a short synthetic method to prepare deuterium and tritium labeled 1 using a ketoreductase enzyme catalyzed reduction as the key step to introduce the label in a highly efficient and enantioselective way.
