102075-35-4Relevant academic research and scientific papers
A facile microwave assisted synthesis of spiro-1,3-oxazines from N-(2-(cyclohex-1-en-1-yl)ethyl)amides
Saikia, Ujwal Pratim,Baruah, Diganta,Pahari, Pallab,Borah, Manash Jyoti,Goswami, Amrit,Konwar, Dilip
supporting information, p. 4328 - 4330 (2014/07/22)
A mild and efficient methodology has been developed for the synthesis of spiro-1,3-oxazine derivatives by the microwave assisted cyclization of N-2-(1′-cyclohexenyl)ethyl-acetamides/benzamides. The reaction was catalyzed by in situ generated trimethylsilyl iodide and featured by its very short reaction time. The starting materials were easily obtained by the condensation of substituted acetic/benzoic acids with 2-(1′-cyclohexenyl) ethyl amine.
Amide-forming ligation of acyltrifluoroborates and hydroxylamines in water
Dumas, Aaron M.,Molander, Gary A.,Bode, Jeffrey W.
supporting information; experimental part, p. 5683 - 5686 (2012/07/01)
Come together, right now: Acyltrifluoroborates and O-benzoyl hydroxylamines come together to form amides in water (see scheme). The ligations are complete within minutes at room temperature and do not require any reagents or catalysts. The reaction has a broad substrate scope and tolerates unprotected functional groups. Copyright
