1020851-86-8

Basic information

• Product Name: 2-cyanoimino-5-ethoxycarbonyl-6-methyl-4-(4-difluoromethoxyphenyl)-3,4-dihydro-1H-pyrimidine
• CAS NO: 1020851-86-8
• Molecular Weight: 350.325
• Mol File: 1020851-86-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-cyanoimino-5-ethoxycarbonyl-6-methyl-4-(4-difluoromethoxyphenyl)-3,4-dihydro-1H-pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-cyanoimino-5-ethoxycarbonyl-6-methyl-4-(4-difluoromethoxyphenyl)-3,4-dihydro-1H-pyrimidine(1020851-86-8)
• EPA Substance Registry System: 2-cyanoimino-5-ethoxycarbonyl-6-methyl-4-(4-difluoromethoxyphenyl)-3,4-dihydro-1H-pyrimidine(1020851-86-8)

Safety Data

• Hazardous Substances Data: 1020851-86-8(Hazardous Substances Data)

Upstream product

• 420-04-2 CYANAMID 
• 73960-07-3 4-difluoromethoxybenzaldehyde 
• 141-97-9 ethyl acetoacetate 

Relevant articles and documents

Cyanamide: a convenient building block to synthesize 4-aryl-2-cyanoimino-3,4-dihydro-1H-pyrimidine systems via a multicomponent reaction

4-Aryl-2-cyanoimino-3,4-dihydro-1H-pyrimidine derivatives were prepared using a multicomponent reaction by reacting a mixture of arene or heteroarenecarbaldehyde, 1,3-dicarbonyl compounds, and cyanamide under acidic conditions. The novelty of this approach derives from its use of cyanamide as a building block in a four-component Biginelli-type reaction. Varying the reaction conditions led to the formation of either N-(2-imino-6-phenyl-1,3,5-oxadiazinan-4-ylidene) cyanamide or 3,4-dihydropyrimidin-2(1H)-one. The type of heterocycle skeleton synthesized depends on the nature of the acid catalyst as well as the reaction conditions employed.