1020853-03-5Relevant articles and documents
A novel tamoxifen derivative, ridaifen-F, is a nonpeptidic small-molecule proteasome inhibitor
Hasegawa, Makoto,Yasuda, Yukari,Tanaka, Makoto,Nakata, Kenya,Umeda, Eri,Wang, Yanwen,Watanabe, Chihiro,Uetake, Shoko,Kunoh, Tatsuki,Shionyu, Masafumi,Sasaki, Ryuzo,Shiina, Isamu,Mizukami, Tamio
, p. 290 - 305 (2014)
In a survey of nonpeptide noncovalent inhibitors of the human 20S proteasome, we found that a novel tamoxifen derivative, RID-F (compound 6), inhibits all three protease activities of the proteasome at submicromolar levels. Structure-activity relationship