26487-67-2

Basic information

• Product Name: 2-(HEXAMETHYLENEIMINO)ETHYL CHLORIDE HYDROCHLORIDE
• Synonyms: 1-(2-chloroethyl)-hexahydro-1h-azepinehydrochloride;hexahydro-1-(2-chloroethyl)-1h-azepinhydrochloride;2-CHLOROETHYLHEXAMETHYLENE IMINE HCL;2-CHLOROETHYLHEXAMETHYLENEMINE HYDROCHLORIDE;2-(HEXAMETHYLENEIMINO)ETHYL CHLORIDE HYDROCHLORIDE;N-(2-CHLOROETHYL)HEXAHYDRO-1H-AZEPINE HYDROCHLORIDE;N-(2-chloroethyl)perhydroazepine hydrochloride;1-(2-Chloroethyl)azepane hydrochloride
• CAS NO: 26487-67-2
• Molecular Formula: C₈H₁₆ClN*ClH
• Molecular Weight: 198.13
• EINECS: 247-733-4
• Product Categories: Miscellaneous
• Mol File: 26487-67-2.mol
• Article Data: 2

Chemical Properties

• Melting Point: 208-210°C
• Boiling Point: 213.3 °C at 760 mmHg
• Flash Point: 82.8 °C
• Appearance: /
• Vapor Pressure: 0.165mmHg at 25°C
• Storage Temp.: Inert atmosphere,Room Temperature
• Sensitive: Hygroscopic
• BRN: 3680388
• CAS DataBase Reference: 2-(HEXAMETHYLENEIMINO)ETHYL CHLORIDE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(HEXAMETHYLENEIMINO)ETHYL CHLORIDE HYDROCHLORIDE(26487-67-2)
• EPA Substance Registry System: 2-(HEXAMETHYLENEIMINO)ETHYL CHLORIDE HYDROCHLORIDE(26487-67-2)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 20/22-36/37-39-52-22-36/38-20
• Safety Statements: 22-26-36/37/39-51-20/21
• RIDADR: 2811
• RTECS: CM3185000
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 26487-67-2(Hazardous Substances Data)

Usage

General Description

2-(Hexamethyleneimino)ethyl chloride hydrochloride is a chemical compound used as a intermediate in the synthesis of various pharmaceuticals and specialty chemicals. It is a quaternary ammonium salt with a molecular formula C8H19Cl2N and a molecular weight of 198.15 g/mol. 2-(HEXAMETHYLENEIMINO)ETHYL CHLORIDE HYDROCHLORIDE is known for its water solubility and is commonly used as a reagent in organic synthesis, particularly in the preparation of quaternary ammonium compound derivatives. Additionally, it is utilized in the production of surfactants, antistatic agents, and other industrial chemicals.

InChI:InChI=1/C8H16ClN.ClH/c9-5-8-10-6-3-1-2-4-7-10;/h1-8H2;1H

Upstream product

• 2205-31-4 1-(2-chloroethyl)-1H-hexahydroazepine 
• 4614-98-6 caprolactam potassium salt 
• 20603-00-3 2-(hexamethyleneimino)ethanol 

Downstream Products

• 678-26-2 perfluoropentane 
• 355-42-0 tetradecafluorohexane 
• 96009-83-5 Perfluoro(N-ethylhexamethyleneimine) 
• 96009-89-1 1-(2-Chloro-1,1,2,2-tetrafluoro-ethyl)-2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-azepane 
• 14176-07-9 2-(hexahydro-1H-azepin-1-yl)ethyl phenyl-3-thienylethanoate 
• 645400-94-8 1-[4-(2-azepan-1-yl-ethoxy)-phenyl]-6-methoxy-1-methyl-2-phenyl-1,2,3,4-tetrahydro-isoquinoline 
• 82874-17-7 2-(2-perhydroazepin-1-ylethylthio)-5-(2-chlorophenyl)-7-chloro-3H-1,4-benzodiazepine fumarate 
• 1206894-23-6 1-(2-(4-((1-benzyl-1H-pyrrol-2-yl)(4-methoxyphenyl)methyl)phenoxy)ethyl)azepane 
• 1225208-10-5 C₁₇H₂₄ClN₃O 
• 1225208-16-1 C₁₈H₂₇N₃O 
• 1225208-21-8 C₁₈H₂₄F₃N₃O 
• 1225208-19-4 C₁₈H₂₇N₃O₂ 
• 1225208-12-7 C₁₇H₂₃Cl₂N₃O 
• 1225208-14-9 C₁₈H₂₇N₃O 

Relevant articles and documents

A N-(2-chloroethyl) hexamethylene imine hydrochloride synthetic method

The invention discloses a new synthetic method of N-(2-chloroethyl) hexamethyleneimine hydrochloride. The method comprises the following steps: by taking the caprolactam sylvite as a raw material, performing alkylation, reducing and salifying to obtain the N-(2-chloroethyl) hexamethyleneimine hydrochloride, wherein the total yield is greater than 71% and the product purity is greater than 98.5%. The method has the advantages that the final product N-(2-chloroethyl) hexamethyleneimine hydrochloride is obtained by directly performing alkylation on the caprolactam sylvite, performing reduction reaction on the sodium borohydride and salifying with the hydrogen chloride gas under the condition of taking the isopropanol as a solvent. The product has a high purity without refining.