102088-41-5Relevant academic research and scientific papers
Synthesis of 1,4-Diketones via Titanium-Mediated Reductive Homocoupling of α-Haloketones
Le, Nathan N.,Rodriguez, Aimee M.,Alleyn, James R.,Gesinski, Michael R.
, p. 2195 - 2198 (2018)
1,4-Diketones have been synthesized via a reductive homocoupling of α-haloketones. Addition of a Grignard reagent to titanium(IV) isopropoxide affords a low-valent titanium(III) intermediate that is believed to mediate a radical dimerization reaction. The
Copper(I)/DDQ-Mediated Double-Dehydrogenative Diels-Alder Reaction of Aryl Butenes with 1,4-Diketones and Indolones
Chen, Jie,Hu, Wei,Wang, Min,Xu, Wen-Lei,Zhao, Wei-Ming,Zhou, Ling
supporting information, p. 7169 - 7174 (2020/10/12)
A copper(I)/DDQ-mediated double-dehydrogenative Diels-Alder (DDDA) reaction of simple butenes with 1,4-diketones and indolones has been established for the first time. This strategy is based on a tandem double-dehydrogenation/Diels-Alder reaction from nonprefunctionalized starting materials, in which both a diene and dienophile were in situ generated via activation of fourfold inert C(sp3)-H bonds in one catalytic system.
Mukaiyama-Michael reactions with trans-2,5-diarylpyrrolidine catalysts: Enantioselectivity arises from attractive noncovalent interactions, not from steric hindrance
Kemppainen, Eeva K.,Sahoo, Gokarneswar,Piisola, Antti,Hamza, Andrea,Kotai, Bianka,Papai, Imre,Pihko, Petri M.
, p. 5983 - 5993 (2014/05/20)
The scope of the enantioselective Mukaiyama-Michael reactions catalyzed by trans-2,5-diphenylpyrrolidine has been expanded to include both α- and β-substituted enals. However, the rationalization of the observed enantioselectivity is far from obvious sinc
NEW AND EFFICIENT DEHALOGENATIVE COUPLING AND REDUCTION OF α-HALOKETONES WITH ACTIVE NICKEL COMPLEX. FACILE SYNTHESES OF 1,4-DIKETONES AND BICYCLOOCT-3-ENE-2,5-DIONES
Iyoda, Masahiko,Sakaitani, Masahiro,Kojima, Atsuko,Oda, Masaji
, p. 3719 - 3722 (2007/10/02)
The active nickel complex generated in situ by reduction of NiBr2(PPh3)2 with zinc in the presence of Et4NI is a useful reagent for the dehalogenative coupling of phenacyl halides to 1,4-diaryl-1,4-diketones and for the dechlorination of 3,4-dichlorobicyclo-octane-2,5-diones to bicyclooct-3-ene-2,5-diones.
