1021-20-1

Basic information

• Product Name: trifuran-2-ylphosphane oxide
• CAS NO: 1021-20-1
• Molecular Formula: C₁₂H₉O₄P
• Molecular Weight: 248.1712
• Mol File: 1021-20-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 411°C at 760 mmHg
• Flash Point: 202.4°C
• Density: 1.35g/cm³
• Vapor Pressure: 1.37E-06mmHg at 25°C
• Refractive Index: 1.572
• CAS DataBase Reference: trifuran-2-ylphosphane oxide(CAS DataBase Reference)
• NIST Chemistry Reference: trifuran-2-ylphosphane oxide(1021-20-1)
• EPA Substance Registry System: trifuran-2-ylphosphane oxide(1021-20-1)

Safety Data

• Hazardous Substances Data: 1021-20-1(Hazardous Substances Data)

Upstream product

• 5518-52-5 trifuran-2-yl-phosphane 

Downstream Products

• 5518-52-5 trifuran-2-yl-phosphane 
• 65887-64-1 di-2-furanylphosphinic acid 
• 264625-59-4 1-(2-bromophenyl)ethyl di-2-furanylphosphinate 
• 264625-58-3 (2-bromophenyl)methyl di-2-furanylphosphinate 
• 93973-56-9 di-2-furanylphosphinic chloride 

Relevant articles and documents

Efficient aerobic oxidation of phosphines, phosphites, and sulfides by using trialkylborane

Treatment of phosphines, phosphites, or sulfides with trialkylborane under air afforded the corresponding oxides in good yields.

A Wittig reaction with 2-furyl substituents at the phosphorus atom: Improved (Z) selectivity and isolation of a stable oxaphosphetane intermediate

Wittig reactions with ylides bearing one, two or three 2-furyl groups directly bound to the phosphorus atom have been studied. Greatly improved (Z)-alkene selectivities of up to 98:2 could be observed if 2-furyl groups were present. Monitoring of the reactions by NMR spectroscopy revealed only oxaphosphetane intermediates, which became more stable with increasing number of 2-furyl substituents bound to the phosphorus atom. Oxaphosphetane 10d, with three furyl groups, was successfully isolated, and the results of a crystal structure analysis are presented. Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002.

The Trityl-Cation Mediated Phosphine Oxides Reduction

Reduction of phosphine oxides into the corresponding phosphines using PhSiH3 as a reducing agent and Ph3C+[B(C6F5)4]? as an initiator is described. The process is highly efficient, reducing a broad range of secondary and tertiary alkyl and arylphosphines, bearing various functional groups in generally good yields. The reaction is believed to proceed through the generation of a silyl cation, which reaction with the phosphine oxide provides a phosphonium salt, further reduced by the silane to afford the desired phosphine along with siloxanes. (Figure presented.).