5518-52-5

Basic information

• Product Name: TRI(2-FURYL)PHOSPHINE
• Synonyms: SALOR-INT L308749-1EA;TRIS(2-FURYL)PHOSPHINE;TRI(2-FURYL)PHOSPHINE;Tri(2-furyl)phosphine,97%;Tri-2-furylphosphine,98+%;TRI-(2-FURYL)PHOSPHINE 98%;2,2',2''-Phosphinidynetrisfuran;Tri(2-furanyl)phosphine
• CAS NO: 5518-52-5
• Molecular Formula: C₁₂H₉O₃P
• Molecular Weight: 232.17
• EINECS: 1312995-182-4
• Product Categories: Ligand;Phosphine Ligands;Synthetic Organic Chemistry;Catalysis and Inorganic Chemistry;Phosphine Ligands;Phosphorus Compounds;organophosphorus ligand;Aromatics;Chelating Agents & Ligands;Heterocycles;Achiral Phosphine;Aryl Phosphine
• Mol File: 5518-52-5.mol
• Article Data: 10

Chemical Properties

• Melting Point: 59-64 °C(lit.)
• Boiling Point: 136 °C4 mm Hg(lit.)
• Flash Point: 136°C/4mm
• Appearance: faintly brown/solid
• Vapor Pressure: 0.00456mmHg at 25°C
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Sensitive: air sensitive
• BRN: 1577564
• CAS DataBase Reference: TRI(2-FURYL)PHOSPHINE(CAS DataBase Reference)
• NIST Chemistry Reference: TRI(2-FURYL)PHOSPHINE(5518-52-5)
• EPA Substance Registry System: TRI(2-FURYL)PHOSPHINE(5518-52-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-24/25
• WGK Germany: 3
• F: 10-23
• TSCA: No
• Hazardous Substances Data: 5518-52-5(Hazardous Substances Data)

Usage

Reaction

Useful ligand for C-C coupling reactions. Ligand used for the alkynylation of thioesters. Ligand used for enol ester formation. Ligand for palladium-catalyzed 3-Component coupling. Ligand for palladium-catalyzed C-C coupling reaction. Ligand for trans-olefin formation. Olefin formation from N-tosylhydrazones and benzyl halides. C-H arylation/alkenylation of 1-substituted tetrazoles.

Chemical Properties

TRI(2-FURYL)PHOSPHINE is white to light yellow crystal powde

Uses

Different sources of media describe the Uses of 5518-52-5 differently. You can refer to the following data:
1. TRI(2-FURYL)PHOSPHINE is a phopshine ligand used in transition-metal mediated organic synthesis, in particular in wittig reactions to improved (Z) selectivity.
2. suzuki reaction
3. A phopshine ligand used in transition-metal mediated organic synthesis, in particular in wittig reactions to improved (Z) selectivity.

InChI:InChI=1/C12H9O3P/c1-4-10(13-7-1)16(11-5-2-8-14-11)12-6-3-9-15-12/h1-9H

Upstream product

• 110-00-9 furan 
• 64-17-5 ethanol 
• 1186392-97-1 tris(2-furyl)phosphane-borane(1:1) 
• 1021-20-1 tris(furan-2-yl)phosphine oxide 
• 472962-98-4 Ag(tris(2-furyl)phosphine)3(ONO₂) 
• 2786-02-9 2-lithiofuran 

Downstream Products

• 251966-59-3 1-[3-(2,4-Difluoro-benzyl)-phenyl]-ethanone 
• 252749-95-4 3-(2-fluorophenyl)-5-(2-methyl-2H-1,2,4-triazol-3-ylmethoxy)-6-(2,2-dimethylpropyl)-1,2,3-triazolo[4,5-b]pyridine 
• 189810-00-2 2-amino-5-{2-[1-(4-chlorophenyl)cyclopentyl]vinyl}-6-methyl-4-pyrimidinylamine 
• 761446-35-9 4-Methoxy-7-(3-hydroxy-1-butyn-1-yl)-6-azaindole 
• 676490-52-1 1-[4-(1-phenyl-1-(2-isopropylethyn-1-yl)-methylene)-piperidin-1-yl]-2-(4,7-dimethoxy-6-azaindol-3-yl)-ethane-1,2-dione 
• 91311-62-5 [Os3(CO)10(μ-bis(diphenylphosphino)methane)] 

Relevant articles and documents

Synthesis of the tertiaryphosphine derivatives of iron carbonyl phosphines: preparation of tetracarbonyliron(0), pentacarbonylbisdiiron(0), tetracarbonyliron(0) and pentacarbonylbis<...

Pentacarbonyl iron reacts with this(2-furyl)phosphine (or tris(2-benzofuryl)phosphine) in the presence of sodium borohydride in refluxing n-butanol to give the title compounds.The crystal and molecular structure of pentacarbonylbis(μ-bis(2-furyl)phosphido>diiron(0) were determined by X-ray crystallography. Keywords: Iron; Dinuclear; Carbonyls; X-ray structure; Benzoferrylphosphine complex

The Trityl-Cation Mediated Phosphine Oxides Reduction

Reduction of phosphine oxides into the corresponding phosphines using PhSiH3 as a reducing agent and Ph3C+[B(C6F5)4]? as an initiator is described. The process is highly efficient, reducing a broad range of secondary and tertiary alkyl and arylphosphines, bearing various functional groups in generally good yields. The reaction is believed to proceed through the generation of a silyl cation, which reaction with the phosphine oxide provides a phosphonium salt, further reduced by the silane to afford the desired phosphine along with siloxanes. (Figure presented.).

Catalyst-free alcoholysis of phosphane-boranes: a smooth, cheap, and efficient deprotection procedure

Catalyst-free alcoholytic deprotection of borane-protected phosphorus compounds offers a smooth, efficient, and clean alternative to existing deprotection methods. In this paper we report our results on the general applicability of deprotecting phosphane-