10212-19-8

Usage

Uses

2''-Chloro-2''-deoxycytidine is a nucleoside derivative.

Upstream product

• 745814-57-7 N⁴-acetyl-3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-2'-chloro-2'-deoxycytidine 
• 401812-85-9 N⁴-acetyl-1-[3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-2-O-(trifluoromethanesulfonyl)-β-D-arabinofuranosyl]cytosine 
• 161601-95-2 N⁴-acetyl-1-[3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-D-arabinofuranosyl]cytosine 
• 75331-99-6 1-[3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-β-D-arabinofuranosyl]cytosine 

Relevant academic research and scientific papers

A packing-density metric for exploring the interior of folded RNA molecules

The intricate architectures of RNA molecules often contain expansive close-packed interfaces. The folding of the well-defined P4-P6 RNA domain was challenged by using a series of 2′-modified nucleotides with a narrow range of molecular volumes. The resulting folding interferences (see picture) reflect the spatial environment of the 2′-hydroxy groups and thereby define a packing-density metric.