1021340-55-5Relevant academic research and scientific papers
Efficient, selective, and green: Catalyst tuning for highly enatioselective reactions of ethylene
Smith, Craig R.,Rajanbabu
, p. 1657 - 1659 (2008)
Fine tuning of the biaryl and amino moieties of Feringa's phosphoramidite ligands yields structurally simpler, yet more efficient and selective, ligands for asymmetric hydrovinylation of vinylarenes and acylic 1,3-dienes. The enantioselectivities and yields observed in the formation of the 3-arylbutenes are among the highest for all asymmetric catalytic processes reported to date for the synthesis of intermediates for the widely used antiinflammatory 2-arylpropionic acids including naproxen, ibuprofen, fenoprofen, and flurbiprofen.
