1021389-89-8

Upstream product

• 143090-18-0 tert-butyl N-(4-cyanophenyl)carbamate 
• 73096-38-5 N-(4-(1H-tetrazol-5-yl)phenyl)acetamide 
• 35704-19-9 N-(4-cyanophenyl)acetamide 
• 873-74-5 4-Aminobenzonitrile 
• 1021389-87-6 [4-(1H-tetrazol-5-yl)-phenyl]-carbamic acid tert-butyl ester 

Downstream Products

• 46047-18-1 4-(1H-tetrazol-5-yl)aniline 

Relevant academic research and scientific papers

New tetrazolic azo dyes linked to (thio)barbiturate and electron-rich aromatics as potential antimicrobial agents

A series of new tetrazolic azo dyes based on (thio)barbiturate and electron-rich aromatics were synthesized in excellent yield. The electron-donor and tetrazole ring moieties were linked by a p-phenylazo bridge and the structural characterizations were achieved by FT IR, 1H and 13C NMR, and UV-visible spectrometry. The antibacterial activity of the synthesized compounds was tested against gram-positive and gram-negative bacterial strains, namely Acinetobacter calcoaceticus (ATCC23055), Escherichia coli (ATCC2592), Pseudomonas aeruginosa (ATCC27853), and Staphylococcus aureus (ATCC25923). As a result, potential antimicrobial effects were seen for some of the synthesized compounds.

INDAZOLE DERIVATIVES

The invention is concerned with novel indazole derivatives of formula (I) wherein R1, R2, R3, R4, R5, R6, X and Y are as defined in the description and in the claims, as well as physiologic