1021432-70-1

Basic information

• Product Name: χ,χ-caroten-18,18-dioic acid
• Synonyms: χ,χ-caroten-18,18-dioic acid
• CAS NO: 1021432-70-1
• Molecular Weight: 588.787
• Mol File: 1021432-70-1.mol

Chemical Properties

• CAS DataBase Reference: χ,χ-caroten-18,18-dioic acid(CAS DataBase Reference)
• NIST Chemistry Reference: χ,χ-caroten-18,18-dioic acid(1021432-70-1)
• EPA Substance Registry System: χ,χ-caroten-18,18-dioic acid(1021432-70-1)

Safety Data

• Hazardous Substances Data: 1021432-70-1(Hazardous Substances Data)

Upstream product

• 1333231-03-0 C₁₁H₁₁F₃O₅S 
• 1333231-04-1 C₁₅H₂₁BO₄ 
• 1333231-00-7 C₆H₂(CH₃)2(C(O)OCH₃)(C₂H₂C(CH₃)CHI) 
• 1301147-34-1 C₁₀H₁₃BrO₂ 
• 56798-08-4 (E)-1-bromo-2-iodoethylene 
• 1333231-02-9 C₁₁H₁₄O₄ 
• 22802-37-5 4-bromo-2,3-dimethylphenol 
• 1427286-48-3 (3E,5E,7E)-8-iodo-4-methylnona-1,3,5,7-tetraene 
• 1427286-47-2 (2E,4E,6E)-7-iodo-3-methylocta-2,4,6-trienal 
• 1427286-46-1 (2E,4E,6E)-3-methyl-7-tributylstannylocta-2,4,6-trienal 
• 1058725-45-3 dimethyl (1E,3E,5E,7E,9E,11E,13E,15E,17E) 4,4'-(3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaene-1,18-diyl)-bis-(2,3-dimethylbenzoate) 
• 1427286-58-5 methyl (E)-2,3-dimethyl-4-(2-(tributylstannyl)vin-1-yl)benzoate 
• 1427286-50-7 (2E,4E,6E,8E,10E,12E,14E)-2,15-diiodo-6,11-dimethylhexadeca-2,4,6,8,10,12,14-heptaene 
• 1427286-57-4 methyl 4-ethynyl-2,3-dimethylbenzoate 

Downstream Products

• 1058725-46-4 (all-E)-18,18'-dihydroxy-χ,χ-carotene 
• 1058725-45-3 dimethyl (1E,3E,5E,7E,9E,11E,13E,15E,17E) 4,4'-(3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaene-1,18-diyl)-bis-(2,3-dimethylbenzoate) 

Relevant articles and documents

A conjunctive diiodoheptaene for the synthesis of C2-symmetric carotenoids

(2E,4E,6E,8E,10E,12E,14E)-2,15-Diiodo-6,11-dimethylhexadeca-2,4,6,8,10,12, 14-heptaene, prepared by homometathesis, has been used in palladium-catalyzed Suzuki and Stille cross-coupling reactions with the appropriate partners to construct the C2-symmetric carotenoids β,β-carotene, lycopene, synechoxanthin and 4,4′-diapo-ψ,ψ-carotene-4,4′- dial. The Royal Society of Chemistry 2013.

Total synthesis of synechoxanthin through iterative cross-coupling

The choice is yours: The first total synthesis of the antioxidant carotenoid synechoxanthin was achieved through a novel iterative cross-coupling approach in which the polarity of the bifunctional building blocks is reversed to match the preferred polarity for C-C bond formation (see scheme). The convergent, stereocontrolled, and flexible nature of this synthesis enables systematic studies of the biological activities of this natural product.