1301147-34-1Relevant academic research and scientific papers
Total synthesis of synechoxanthin through iterative cross-coupling
Fujii, Seiko,Chang, Stephanie Y.,Burke, Martin D.
, p. 7862 - 7864 (2011)
The choice is yours: The first total synthesis of the antioxidant carotenoid synechoxanthin was achieved through a novel iterative cross-coupling approach in which the polarity of the bifunctional building blocks is reversed to match the preferred polarity for C-C bond formation (see scheme). The convergent, stereocontrolled, and flexible nature of this synthesis enables systematic studies of the biological activities of this natural product.
