1021461-99-3Relevant academic research and scientific papers
Synthesis of β-C-glycopyranosyl-1,4-naphthoquinone derivatives and their cytotoxic activity
Lin, Li,He, Xiao-Peng,Xu, Qing,Chen, Guo-Rong,Xie, Juan
, p. 773 - 779 (2008/09/21)
β-C-Glucosyl and β-C-galactosyl-1,4-dimethoxynaphthalenes have been synthesized using a F3CCO2Ag/SnCl4 promoted Friedel-Crafts electrophilic substitution reaction. Both glycosyl acetates and methyl glycosides can be used as glycosyl donors. Further oxidation afforded the corresponding β-C-glycosyl-1,4-naphthoquinones. The in vitro cytotoxic activity of these compounds was evaluated against the A375 cell line.
