1021464-54-9Relevant academic research and scientific papers
Synthesis of sulfonamides and evaluation of their histone deacetylase (HDAC) activity
Oh, Seikwan,Moon, Hyung-In,Son, Il-Hong,Jung, Jae-Chul
, p. 1125 - 1135 (2008/02/05)
A simple synthesis of sulfonamides 4-22 as novel histone deacetylase (HDAC) inhibitors is described. The key synthetic strategies involve N-sulfonylation of L-proline benzyl ester hydrochloride (2) and coupling reaction of N-sulfonyl chloride 3 with amine
