1021486-53-2

Upstream product

• 52056-69-6 2-[(11-bromoundecyl)oxy]tetrahydro-2H-pyran 
• 73010-80-7 1-tetrahydropyranyloxyundecyl-11-triphenylphosphonium bromide 
• 2859-67-8 3-(3-pyridyl)propan-1-ol 
• 1802-16-0 3-(3-pyridinyl)propionaldehyde 
• 133850-33-6 (Z)-1-tetrahydropyran-2'-yloxy-14-(pyridin-3''-yl)tetradec-11-ene 
• 133835-21-9 (Z)-14-(pyridin-3'-yl)tetradec-11-en-1-ol 
• 133835-22-0 (Z)-14-(pyridin-3′-yl)tetradec-11-enal 
• 492-38-6 2-phenylacrylic acid 
• 1396008-61-9 (R)-3-(2-phenylacryloyl)-4-isopropyl-5,5-dimethyloxazolidin-2-one 
• 1396008-63-1 (4R)-3-[(2S)-2-phenyl-3-(N-benzylamino)propanoyl]-4-isopropyl-5,5-dimethyloxazolidin-2-one 
• 1611-56-9 1-Bromo-11-hydroxyundecane 

Downstream Products

• 1021319-14-1 C₃₇H₄₉N₃O₃ 
• 1021319-11-8 C₃₇H₄₉N₃O₃ 

Relevant academic research and scientific papers

Asymmetric synthesis of the marine alkaloid (-)-(S)-nakinadine C

The first asymmetric synthesis of the marine alkaloid (-)-(S)-nakinadine C is described. This synthesis employs the conjugate addition of lithium dibenzylamide to an N-α-phenylacryloyl SuperQuat derivative followed by diastereoselective protonation of the intermediate enolate using 2-pyridone as the key step to introduce the stereochemistry. (-)-(S)-Nakinadine C was isolated in 13% yield over 9 steps from commercially available atropic acid, 98:2 dr [(Z):(E) ratio] and >99% ee.