102162-40-3

Upstream product

• 945410-09-3 ethyl (E)-5-benzylsulfanylpent-2-enoate 
• 122538-55-0 5-benzylsulfanyl-pent-2-enoic acid ethyl ester 
• 100-53-8 phenylmethanethiol 
• 122538-56-1 3,5-bis-benzylsulfanyl-pentanoic acid ethyl ester 

Downstream Products

• 36305-11-0 2-(1,2-dithiolan-3-yl)acetic acid 
• 122538-58-3 3,5-bis(benzylthio)-N,N-dimethylpentylamine 
• 122538-57-2 3,5-bis(benzylthio)-N,N-dimethylvaleramide 

Relevant academic research and scientific papers

DEUTERATED DERIVATIVES OF 6,8-BIS(BENZYLSULFANYL)OCTANOIC ACID

The invention provides new deuterated derivatives of 6,8-bis(benzylsulfanyl)octanoic acid, pharmaceutical compositions thereof, and methods for treating cancer with the new compositions.

1,2-DITHIOLANE AND DITHIOL COMPOUNDS USEFUL IN TREATING MUTANT EGFR-MEDIATED DISEASES AND CONDITIONS

Compositions of the invention comprise 1,2-dithiolane, dithiol and related compounds useful as therapeutic agents for the treatment and prevention of diseases and conditions associated with aberrant EGFR activity.

1,2-DITHIOLANE AND DITHIOL COMPOUNDS USEFUL IN TREATING MUTANT EGFR-MEDIATED DISEASES AND CONDITIONS

Compositions of the invention comprise 1,2-dithiolane, dithiol and related compounds useful as therapeutic agents for the treatment and prevention of diseases and conditions associated with aberrant EGFR activity.

Synthesis and Biological Activity of 1,2-Dithiolanes and 1,2-Dithianes Bearing a Nitrogen-containing Substituent

A series of 1,2-dithiolanes, 1,2-dithianes and related compounds bearing a nitrogen-containing substituent were synthesized and their pesticidal activity was tested.A new general synthetic route to 1,2-dithiolanes was established from 1,3-diols.A variation in the position and character of the nitrogen atom is shown to be allowable to some extent for promoting insecticidal activity, unlike the case of sulfur atoms.Most compounds showed acaricidal activity, the strongest being displayed by cis-3,5-bis(dimethylaminomethyl)-1,2-dithiolane.