102183-41-5

Upstream product

• 34177-11-2 3-chloro-5,6-diphenyl-1,2,4-triazine 
• 118-92-3 anthranilic acid 
• 93119-96-1 3,4-diphenyl-2H-isoquinolin-1-one 
• 102467-48-1 2-(α'-chloro-stilben-α-yl)-benzoic acid amide 

Downstream Products

• 52839-45-9 3,4-diphenylisoquinoline 

Relevant academic research and scientific papers

SYNTHESIS OF 1-SUBSTITUTED 3,4-DIARYLISOQUINOLINE DERIVATIVES

3,4-Diaryl-2H-isoquinolin-2-ones and corresponding 1-chloro derivatives were easily prepared in a way involving i) condensation of 2-aroylbenzyl chlorides with arylmethylamines; ii) treatment of the resulting 1-aryl-N-1-hydroxyarylmethylisoindol-3-ones wi

Synthesis of Isoquinolines by Cycloaddition of Arynes to 1,2,4-Triazines

Benzyne has been generated from benzenediazonium-2-carboxylate in the presence of several 1,2,4-triazines 1 and isoquinolines 2 have been isolated in moderate yield. 1-Aminobenzotriazole was also used as the source of benzyne and isoquinolines were again isolated in moderate yield from these reactions. 4-Methylbenzyne, which was generated from 5-methylanthranilic acid, reacted unselectively with the triazines to give mixtures of 6- and 7-methylisoquinolines 3 and 4.On the other hand reactions of 3-methylbenzyne with the triazines 1d and 1e proceeded with high regioselectivity, giving only the 5-methylisoquinoline 5a and the 8-methylisoquinoline 6b, respectively.