1022159-94-9

Basic information

• Product Name: 3-hydroxy-5-[{4-(3-phenylureido)phenylamino}methyl]benzoic acid
• Synonyms: 3-hydroxy-5-[{4-(3-phenylureido)phenylamino}methyl]benzoic acid
• CAS NO: 1022159-94-9
• Molecular Weight: 377.4
• Mol File: 1022159-94-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-hydroxy-5-[{4-(3-phenylureido)phenylamino}methyl]benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxy-5-[{4-(3-phenylureido)phenylamino}methyl]benzoic acid(1022159-94-9)
• EPA Substance Registry System: 3-hydroxy-5-[{4-(3-phenylureido)phenylamino}methyl]benzoic acid(1022159-94-9)

Safety Data

• Hazardous Substances Data: 1022159-94-9(Hazardous Substances Data)

Upstream product

• 10141-46-5 1–(4-aminophenyl)-3-phenylurea 
• 1022160-01-5 3-carboxy-5-hydroxybenzaldehyde 

Relevant articles and documents

De novo Design and synthesis of N-benzylanilines as new candidates for VEGFR tyrosine kinase inhibitors

N-Benzylanilines were designed and synthesized as vascular endothelial growth factor (VEGF)-2 inhibitors using de novo drug design systems based on the X-ray structure of VEGFR-2 kinase domain. Among compounds synthesized, compound 3 showed the most potent inhibitory activity toward VEGFR-2 (KDR) tyrosine kinase and its IC50 value was 0.57 μM.