1022159-96-1

Basic information

• Product Name: 1-[4-(3,5-dihydroxybenzylamino)phenyl]-3-phenylurea
• Synonyms: 1-[4-(3,5-dihydroxybenzylamino)phenyl]-3-phenylurea
• CAS NO: 1022159-96-1
• Molecular Weight: 349.389
• Mol File: 1022159-96-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[4-(3,5-dihydroxybenzylamino)phenyl]-3-phenylurea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-(3,5-dihydroxybenzylamino)phenyl]-3-phenylurea(1022159-96-1)
• EPA Substance Registry System: 1-[4-(3,5-dihydroxybenzylamino)phenyl]-3-phenylurea(1022159-96-1)

Safety Data

• Hazardous Substances Data: 1022159-96-1(Hazardous Substances Data)

Upstream product

• 26153-38-8 3,5-dihydroxybenzaldehyde 
• 10141-46-5 1–(4-aminophenyl)-3-phenylurea 

Relevant articles and documents

De novo Design and synthesis of N-benzylanilines as new candidates for VEGFR tyrosine kinase inhibitors

N-Benzylanilines were designed and synthesized as vascular endothelial growth factor (VEGF)-2 inhibitors using de novo drug design systems based on the X-ray structure of VEGFR-2 kinase domain. Among compounds synthesized, compound 3 showed the most potent inhibitory activity toward VEGFR-2 (KDR) tyrosine kinase and its IC50 value was 0.57 μM.